Editorial:

Gerald Weissmann

Tithonus and the Fruit Fly: New Science and Old Myths
FASEB J. 2008 22: 1619-1622. [Full Text] [PDF]  

Reviews:

Robert D. Wells

DNA triplexes and Friedreich ataxia
FASEB J. 2008 22: 1625-1634. [Abstract] [Full Text] [PDF]  

Research Communications:

Zhaodi Gong and Laura E. Niklason

Small-diameter human vessel wall engineered from bone marrow-derived mesenchymal stem cells (hMSCs)
FASEB J. 2008 22: 1635-1648. [Abstract] [Full Text] [PDF]  

Nan Xia, Charles K. Thodeti, Tom P. Hunt, Qiaobing Xu, Madelyn Ho, George M. Whitesides, Robert Westervelt, and Donald E. Ingber

Directional control of cell motility through focal adhesion positioning and spatial control of Rac activation
FASEB J. 2008 22: 1649-1659. [Abstract] [Full Text] [PDF] Supplemental Data  

Leigh C. Carmody, Anthony J. Baucum, II, Martha A. Bass, and Roger J. Colbran

Selective targeting of the 1 isoform of protein phosphatase 1 to F-actin in intact cells requires multiple domains in spinophilin and neurabin
FASEB J. 2008 22: 1660-1671. [Abstract] [Full Text] [PDF]  

Mirjam Christ-Crain, Blerina Kola, Francesca Lolli, Csaba Fekete, Dalma Seboek, Gábor Wittmann, Daniel Feltrin, Susana C. Igreja, Sharon Ajodha, Judith Harvey-White, George Kunos, Beat Müller, Francois Pralong, Gregory Aubert, Giorgio Arnaldi, Gilberta Giacchetti, Marco Boscaro, Ashley B. Grossman, and Márta Korbonits

AMP-activated protein kinase mediates glucocorticoid-induced metabolic changes: a novel mechanism in Cushing’s syndrome
FASEB J. 2008 22: 1672-1683. [Abstract] [Full Text] [PDF]  

Paul A. Clark, Eduardo K. Moioli, D. Rick Sumner, and Jeremy J. Mao

Porous implants as drug delivery vehicles to augment host tissue integration
FASEB J. 2008 22: 1684-1693. [Abstract] [Full Text] [PDF]  

Jody M. Lingbeck, Julie S. Trausch-Azar, Aaron Ciechanover, and Alan L. Schwartz

In vivo interactions of MyoD, Id1, and E2A proteins determined by acceptor photobleaching fluorescence resonance energy transfer
FASEB J. 2008 22: 1694-1701. [Abstract] [Full Text] [PDF]  

Thorsten Lau, Sandra Horschitz, Stefan Berger, Dusan Bartsch, and Patrick Schloss

Antidepressant-induced internalization of the serotonin transporter in serotonergic neurons
FASEB J. 2008 22: 1702-1714. [Abstract] [Full Text] [PDF]  

Heather C. Maisey, Darin Quach, Mary E. Hensler, George Y. Liu, Richard L. Gallo, Victor Nizet, and Kelly S. Doran

A group B streptococcal pilus protein promotes phagocyte resistance and systemic virulence
FASEB J. 2008 22: 1715-1724. [Abstract] [Full Text] [PDF]  

Katie Shorter, Nilofer P. Farjo, Steven M. Picksley, and Valerie A. Randall

Human hair follicles contain two forms of ATP-sensitive potassium channels, only one of which is sensitive to minoxidil
FASEB J. 2008 22: 1725-1736. [Abstract] [Full Text] [PDF]  

Adil A. Khan, Xiao Ou Mao, Surita Banwait, Celine M. DerMardirossian, Gary M. Bokoch, Kunlin Jin, and David A. Greenberg

Regulation of hypoxic neuronal death signaling by neuroglobin
FASEB J. 2008 22: 1737-1747. [Abstract] [Full Text] [PDF]  

Retraction
FASEB J. 2008 22: 1748-1755. [Full Text] [PDF]  

Luca Grumolato, Hafida Ghzili, Maité Montero-Hadjadje, Stéphane Gasman, Jean Lesage, Yannick Tanguy, Ludovic Galas, Djida Ait-Ali, Jérôme Leprince, Nathalie C. Guérineau, Abdel G. Elkahloun, Alain Fournier, Didier Vieau, Hubert Vaudry, and Youssef Anouar

Selenoprotein T is a PACAP-regulated gene involved in intracellular Ca²⁺ mobilization and neuroendocrine secretion
FASEB J. 2008 22: 1756-1768. [Abstract] [Full Text] [PDF]  

Melinda C. Cushing, Peter D. Mariner, Jo-Tsu Liao, Evan A. Sims, and Kristi S. Anseth

Fibroblast growth factor represses Smad-mediated myofibroblast activation in aortic valvular interstitial cells
FASEB J. 2008 22: 1769-1777. [Abstract] [Full Text] [PDF]  

Haiying Yu, Melanie Königshoff, Aparna Jayachandran, Dan Handley, Werner Seeger, Naftali Kaminski, and Oliver Eickelberg

Transgelin is a direct target of TGF-β/Smad3-dependent epithelial cell migration in lung fibrosis
FASEB J. 2008 22: 1778-1789. [Abstract] [Full Text] [PDF]  

Guoli Chen, Xiaoyang Zhou, Persoulla Nicolaou, Patricia Rodriguez, Guojie Song, Bryan Mitton, Anand Pathak, Amit Zachariah, Guo-Chang Fan, Gerald W. Dorn, II, and Evangelia G. Kranias

A human polymorphism of protein phosphatase-1 inhibitor-1 is associated with attenuated contractile response of cardiomyocytes to β-adrenergic stimulation
FASEB J. 2008 22: 1790-1796. [Abstract] [Full Text] [PDF]  

Tetsuya Mizuno, Guiqin Zhang, Hideyuki Takeuchi, Jun Kawanokuchi, Jinyan Wang, Yoshifumi Sonobe, Shijie Jin, Naoki Takada, Yukio Komatsu, and Akio Suzumura

Interferon- directly induces neurotoxicity through a neuron specific, calcium-permeable complex of IFN- receptor and AMPA GluR1 receptor
FASEB J. 2008 22: 1797-1806. [Abstract] [Full Text] [PDF]  

Pankaj K. Bhavsar, Maria B. Sukkar, Nadia Khorasani, Kang-Yun Lee, and Kian Fan Chung

Glucocorticoid suppression of CX₃CL1 (fractalkine) by reduced gene promoter recruitment of NF-B
FASEB J. 2008 22: 1807-1816. [Abstract] [Full Text] [PDF]  

Juan Román Luque-Ortega, Wim van't Hof, Enno C. I. Veerman, José M. Saugar, and Luis Rivas

Human antimicrobial peptide histatin 5 is a cell-penetrating peptide targeting mitochondrial ATP synthesis in Leishmania
FASEB J. 2008 22: 1817-1828. [Abstract] [Full Text] [PDF] Supplemental Data  

Wenfu Tan, Todd R. Palmby, Julie Gavard, Panomwat Amornphimoltham, Yi Zheng, and J. Silvio Gutkind

An essential role for Rac1 in endothelial cell function and vascular development
FASEB J. 2008 22: 1829-1838. [Abstract] [Full Text] [PDF]  

Kaitlyn Kelly, Peter Brader, Avigail Rein, Jatin P. Shah, Richard J. Wong, Yuman Fong, and Ziv Gil

Attenuated multimutated herpes simplex virus-1 effectively treats prostate carcinomas with neural invasion while preserving nerve function
FASEB J. 2008 22: 1839-1848. [Abstract] [Full Text] [PDF]  

Lucia De Franceschi, Orah S. Platt, Giorgio Malpeli, Anne Janin, Aldo Scarpa, Christophe Leboeuf, Yves Beuzard, Emmanuel Payen, and Carlo Brugnara

Protective effects of phosphodiesterase-4 (PDE-4) inhibition in the early phase of pulmonary arterial hypertension in transgenic sickle cell mice
FASEB J. 2008 22: 1849-1860. [Abstract] [Full Text] [PDF]  

Alexander Stephan, José María Mateos, Serguei V. Kozlov, Paolo Cinelli, Andreas David Kistler, Stefan Hettwer, Thomas Rülicke, Peter Streit, Beat Kunz, and Peter Sonderegger

Neurotrypsin cleaves agrin locally at the synapse
FASEB J. 2008 22: 1861-1873. [Abstract] [Full Text] [PDF]  

Catarina M. Quinzii, Luis C. López, Jakob Von-Moltke, Ali Naini, Sindu Krishna, Markus Schuelke, Leonardo Salviati, Plácido Navas, Salvatore DiMauro, and Michio Hirano

Respiratory chain dysfunction and oxidative stress correlate with severity of primary CoQ₁₀ deficiency
FASEB J. 2008 22: 1874-1885. [Abstract] [Full Text] [PDF]  

Tomotake Tokunou, Rachel Miller, Parth Patwari, Michael E. Davis, Vincent F. M. Segers, Alan J. Grodzinsky, and Richard T. Lee

Engineering insulin-like growth factor-1 for local delivery
FASEB J. 2008 22: 1886-1893. [Abstract] [Full Text] [PDF]  

Alexandre Puissant, Sebastien Grosso, Arnaud Jacquel, Nathalie Belhacene, Pascal Colosetti, Jill-Patrice Cassuto, and Patrick Auberger

Imatinib mesylate-resistant human chronic myelogenous leukemia cell lines exhibit high sensitivity to the phytoalexin resveratrol
FASEB J. 2008 22: 1894-1904. [Abstract] [Full Text] [PDF]  

Kathrin Maedler, Fabienne T. Schulthess, Christelle Bielman, Thierry Berney, Christophe Bonny, Marc Prentki, Marc Y. Donath, and Raphael Roduit

Glucose and leptin induce apoptosis in human β-cells and impair glucose-stimulated insulin secretion through activation of c-Jun N-terminal kinases
FASEB J. 2008 22: 1905-1913. [Abstract] [Full Text] [PDF]  

Tatjana Coric, Yale J. Passamaneck, Ping Zhang, Anna Di Gregorio, and Cecilia M. Canessa

Simple chordates exhibit a proton-independent function of acid-sensing ion channels
FASEB J. 2008 22: 1914-1923. [Abstract] [Full Text] [PDF]  

J. Robert Lane, David Henderson, Ben Powney, Alan Wise, Stephen Rees, Dion Daniels, Chris Plumpton, Ian Kinghorn, and Graeme Milligan

Antibodies that identify only the active conformation of G_i family G protein subunits
FASEB J. 2008 22: 1924-1932. [Abstract] [Full Text] [PDF]  

Christoph Roesli, Viviane Mumprecht, Dario Neri, and Michael Detmar

Identification of the surface-accessible, lineage-specific vascular proteome by two-dimensional peptide mapping
FASEB J. 2008 22: 1933-1944. [Abstract] [Full Text] [PDF] Supplemental Data  

Helen H. N. Yan, Dolores D. Mruk, Will M. Lee, and C. Yan Cheng

Blood-testis barrier dynamics are regulated by testosterone and cytokines via their differential effects on the kinetics of protein endocytosis and recycling in Sertoli cells
FASEB J. 2008 22: 1945-1959. [Abstract] [Full Text] [PDF] Supplemental Data  

Shuo Yang, Xuan Liu, Yanqing Yin, Michiko N. Fukuda, and Jiawei Zhou

Tastin is required for bipolar spindle assembly and centrosome integrity during mitosis
FASEB J. 2008 22: 1960-1972. [Abstract] [Full Text] [PDF] Supplemental Data  

Shinsuke Miyahara, Lama Almulki, Kousuke Noda, Toru Nakazawa, Toshio Hisatomi, Shintaro Nakao, Kennard L. Thomas, Alexander Schering, Souska Zandi, Sonja Frimmel, Faryan Tayyari, Rebecca C. Garland, Joan W. Miller, Evangelos S. Gragoudas, Sharmila Masli, and Ali Hafezi-Moghadam

In vivo imaging of endothelial injury in choriocapillaris during endotoxin-induced uveitis
FASEB J. 2008 22: 1973-1980. [Abstract] [Full Text] [PDF]  

Xiangsheng Zuo, Lanlan Shen, Jean-Pierre Issa, Ofir Moy, Jeffrey S. Morris, Scott M. Lippman, and Imad Shureiqi

15-Lipoxygenase-1 transcriptional silencing by DNA methyltransferase-1 independently of DNA methylation
FASEB J. 2008 22: 1981-1992. [Abstract] [Full Text] [PDF]  

Thierry Voisin, Aadil El Firar, Christiane Rouyer-Fessard, Valérie Gratio, and Marc Laburthe

A hallmark of immunoreceptor, the tyrosine-based inhibitory motif ITIM, is present in the G protein-coupled receptor OX1R for orexins and drives apoptosis: a novel mechanism
FASEB J. 2008 22: 1993-2002. [Abstract] [Full Text] [PDF]  

J. A. McLear, D. Lebrecht, A. Messer, and W. J. Wolfgang

Combinational approach of intrabody with enhanced Hsp70 expression addresses multiple pathologies in a fly model of Huntington’s disease
FASEB J. 2008 22: 2003-2011. [Abstract] [Full Text] [PDF] Supplemental Data  

Benedetta Mattioli, Elisabetta Straface, Paola Matarrese, Maria Giovanna Quaranta, Luciana Giordani, Walter Malorni, and Marina Viora

Leptin as an immunological adjuvant: enhanced migratory and CD8⁺ T cell stimulatory capacity of human dendritic cells exposed to leptin
FASEB J. 2008 22: 2012-2022. [Abstract] [Full Text] [PDF]  

Alfred E. Chappell, Michael Bunz, Eric Smoll, Hui Dong, Christian Lytle, Kim E. Barrett, and Declan F. McCole

Hydrogen peroxide inhibits Ca²⁺-dependent chloride secretion across colonic epithelial cells via distinct kinase signaling pathways and ion transport proteins
FASEB J. 2008 22: 2023-2036. [Abstract] [Full Text] [PDF]  

J. L. Tarry-Adkins, M. S. Martin-Gronert, J.-H. Chen, R. L. Cripps, and S. E. Ozanne

Maternal diet influences DNA damage, aortic telomere length, oxidative stress, and antioxidant defense capacity in rats
FASEB J. 2008 22: 2037-2044. [Abstract] [Full Text] [PDF]  

Xinran Xu, Marilie D. Gammon, Steven H. Zeisel, Yin Leng Lee, James G. Wetmur, Susan L. Teitelbaum, Patrick T. Bradshaw, Alfred I. Neugut, Regina M. Santella, and Jia Chen

Choline metabolism and risk of breast cancer in a population-based study
FASEB J. 2008 22: 2045-2052. [Abstract] [Full Text] [PDF]  

Celine A. Beamer and Andrij Holian

Silica suppresses Toll-like receptor ligand-induced dendritic cell activation
FASEB J. 2008 22: 2053-2063. [Abstract] [Full Text] [PDF]  

Robert-Jan Sanders, Rob Ofman, Georges Dacremont, Ronald J. A. Wanders, and Stephan Kemp

Characterization of the human -oxidation pathway for -hydroxy-very-long-chain fatty acids
FASEB J. 2008 22: 2064-2071. [Abstract] [Full Text] [PDF]  

Eng-Hui Chew, Jun Lu, Tracey D. Bradshaw, and Arne Holmgren

Thioredoxin reductase inhibition by antitumor quinols: a quinol pharmacophore effect correlating to antiproliferative activity
FASEB J. 2008 22: 2072-2083. [Abstract] [Full Text] [PDF]  

S. T. Rashid, B. Fuller, G. Hamilton, and A. M. Seifalian

Tissue engineering of a hybrid bypass graft for coronary and lower limb bypass surgery
FASEB J. 2008 22: 2084-2089. [Abstract] [Full Text] [PDF]  

K. A. Varady, D. J. Roohk, B. K. McEvoy-Hein, B. D. Gaylinn, M. O. Thorner, and M. K. Hellerstein

Modified alternate-day fasting regimens reduce cell proliferation rates to a similar extent as daily calorie restriction in mice
FASEB J. 2008 22: 2090-2096. [Abstract] [Full Text] [PDF]  

Matthieu D. Lavigne, Laura Yates, Peter Coxhead, and Dariusz C. Górecki

Nuclear-targeted chimeric vector enhancing nonviral gene transfer into skeletal muscle of Fabry mice in vivo
FASEB J. 2008 22: 2097-2107. [Abstract] [Full Text] [PDF] Supplemental Data  

Letters to the Editor:

Ervin G. Erdös

Regarding "German science and black racism—roots of the Nazi Holocaust"
FASEB J. 2008 22: 1623. [Full Text] [PDF]  

François Haas

Response to comments by Ervin G. Erdös
FASEB J. 2008 22: 1623a-1624. [Full Text] [PDF]  

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