Editorial:

Gerald Weissmann

Citizen Pinel and the Madman at Bellevue
FASEB J. 2008 22: 1289-1293. [Full Text] [PDF]  

Milestone:

P. Michael Conn and James V. Parker

The animal research war
FASEB J. 2008 22: 1294-1295. [Full Text] [PDF]  

Reviews:

Tamar Amit, Yael Avramovich-Tirosh, Moussa B. H. Youdim, and Silvia Mandel

Targeting multiple Alzheimer’s disease etiologies with multimodal neuroprotective and neurorestorative iron chelators
FASEB J. 2008 22: 1296-1305. [Abstract] [Full Text] [PDF]  

Research Communications:

Zachary M. Sellers, Elizabeth Mann, Anders Smith, Kwang Hyun Ko, Ralph Giannella, Mitchell B. Cohen, Kim E. Barrett, and Hui Dong

Heat-stable enterotoxin of Escherichia coli (STa) can stimulate duodenal HCO₃^– secretion via a novel GC-C- and CFTR-independent pathway
FASEB J. 2008 22: 1306-1316. [Abstract] [Full Text] [PDF]  

Josef Buttigieg, Stephen Brown, Min Zhang, Michael Lowe, Alison C. Holloway, and Colin A. Nurse

Chronic nicotine in utero selectively suppresses hypoxic sensitivity in neonatal rat adrenal chromaffin cells
FASEB J. 2008 22: 1317-1326. [Abstract] [Full Text] [PDF]  

Julia Fuchs, Ales Tichopad, Yulia Golub, Marita Munz, Katherine J. Schweitzer, Björn Wolf, Daniela Berg, Jakob C. Mueller, and Thomas Gasser

Genetic variability in the SNCA gene influences -synuclein levels in the blood and brain
FASEB J. 2008 22: 1327-1334. [Abstract] [Full Text] [PDF]  

Guofei Zhou, Laura A. Dada, Navdeep S. Chandel, Kazuhiro Iwai, Emilia Lecuona, Aaron Ciechanover, and Jacob I. Sznajder

Hypoxia-mediated Na-K-ATPase degradation requires von Hippel Lindau protein
FASEB J. 2008 22: 1335-1342. [Abstract] [Full Text] [PDF] Supplemental Data  

Karel Talavera, Keiko Yasumatsu, Ryusuke Yoshida, Robert F. Margolskee, Thomas Voets, Yuzo Ninomiya, and Bernd Nilius

The taste transduction channel TRPM5 is a locus for bitter-sweet taste interactions
FASEB J. 2008 22: 1343-1355. [Abstract] [Full Text] [PDF] Supplemental Data  

Juan Arredondo, Alexander I. Chernyavsky, David L. Jolkovsky, Kent E. Pinkerton, and Sergei A. Grando

Receptor-mediated tobacco toxicity: acceleration of sequential expression of 5 and 7 nicotinic receptor subunits in oral keratinocytes exposed to cigarette smoke
FASEB J. 2008 22: 1356-1368. [Abstract] [Full Text] [PDF]  

Oliver H. Krämer, Sylvia Müller, Marc Buchwald, Sigrid Reichardt, and Thorsten Heinzel

Mechanism for ubiquitylation of the leukemia fusion proteins AML1-ETO and PML-RAR
FASEB J. 2008 22: 1369-1379. [Abstract] [Full Text] [PDF] Supplemental Data  

Alfredo Menendez, Daniel A. Calarese, Robyn L. Stanfield, Keith C. Chow, Chris N. Scanlan, Renate Kunert, Herman Katinger, Dennis R. Burton, Ian A. Wilson, and Jamie K. Scott

A peptide inhibitor of HIV-1 neutralizing antibody 2G12 is not a structural mimic of the natural carbohydrate epitope on gp120
FASEB J. 2008 22: 1380-1392. [Abstract] [Full Text] [PDF] Supplemental Data  

Melissa Muller, Mandri Obeyesekere, Gordon B. Mills, and Prahlad T. Ram

Network topology determines dynamics of the mammalian MAPK1,2 signaling network: bifan motif regulation of C-Raf and B-Raf isoforms by FGFR and MC1R
FASEB J. 2008 22: 1393-1403. [Abstract] [Full Text] [PDF] Supplemental Data  

Danielle Larouche, Xuemei Tong, Julie Fradette, Pierre A. Coulombe, and Lucie Germain

Vibrissa hair bulge houses two populations of skin epithelial stem cells distinct by their keratin profile
FASEB J. 2008 22: 1404-1415. [Abstract] [Full Text] [PDF]  

Elena Shirokova, Jan Dirk Raguse, Wolfgang Meyerhof, and Dietmar Krautwurst

The human vomeronasal type-1 receptor family— detection of volatiles and cAMP signaling in HeLa/Olf cells
FASEB J. 2008 22: 1416-1425. [Abstract] [Full Text] [PDF] Supplemental Data  

Yanping Gong, Ruihua Zhang, Jinping Zhang, Lin Xu, Feng Zhang, Wei Xu, Ying Wang, Yiwei Chu, and Sidong Xiong

-Dystroglycan is involved in positive selection of thymocytes by participating in immunological synapse formation
FASEB J. 2008 22: 1426-1439. [Abstract] [Full Text] [PDF]  

Mona Dvir-Ginzberg, Tsiona Elkayam, and Smadar Cohen

Induced differentiation and maturation of newborn liver cells into functional hepatic tissue in macroporous alginate scaffolds
FASEB J. 2008 22: 1440-1449. [Abstract] [Full Text] [PDF] Supplemental Data  

Yukio Hiroi, Zhongmin Guo, Yuxin Li, Alan H. Beggs, and James K. Liao

Dynamic regulation of endothelial NOS mediated by competitive interaction with -actinin-4 and calmodulin
FASEB J. 2008 22: 1450-1457. [Abstract] [Full Text] [PDF]  

Dany Gaillard, Fabienne Laugerette, Nicolas Darcel, Abdelghani El-Yassimi, Patricia Passilly-Degrace, Aziz Hichami, Naim Akhtar Khan, Jean-Pierre Montmayeur, and Philippe Besnard

The gustatory pathway is involved in CD36-mediated orosensory perception of long-chain fatty acids in the mouse
FASEB J. 2008 22: 1458-1468. [Abstract] [Full Text] [PDF]  

Robyn A. Sharples, Laura J. Vella, Rebecca M. Nisbet, Ryan Naylor, Keyla Perez, Kevin J. Barnham, Colin L. Masters, and Andrew F. Hill

Inhibition of -secretase causes increased secretion of amyloid precursor protein C-terminal fragments in association with exosomes
FASEB J. 2008 22: 1469-1478. [Abstract] [Full Text] [PDF] Supplemental Data  

Takao Shimazoe, Mitsutaka Morita, Shinichiro Ogiwara, Tomoyoshi Kojiya, Junpei Goto, Masaki Kamakura, Takahiro Moriya, Kazuyuki Shinohara, Soichi Takiguchi, Akira Kono, Kyoko Miyasaka, Akihiro Funakoshi, and Masayuki Ikeda

Cholecystokinin-A receptors regulate photic input pathways to the circadian clock
FASEB J. 2008 22: 1479-1490. [Abstract] [Full Text] [PDF]  

Sang-Ho Choi, Robert Langenbach, and Francesca Bosetti

Genetic deletion or pharmacological inhibition of cyclooxygenase-1 attenuate lipopolysaccharide-induced inflammatory response and brain injury
FASEB J. 2008 22: 1491-1501. [Abstract] [Full Text] [PDF]  

Jun Ho Jeon, Kun-yong Kim, Jae Hyeong Kim, Ahmi Baek, Hyungin Cho, Young Ho Lee, Jong Wan Kim, Dohee Kim, Seung Hyun Han, Jong-Seok Lim, Keun Il Kim, Do Young Yoon, Soo-Hyun Kim, Goo Taeg Oh, Eunjoon Kim, and Young Yang

A novel adipokine CTRP1 stimulates aldosterone production
FASEB J. 2008 22: 1502-1511. [Abstract] [Full Text] [PDF]  

William A. Ricke, Stephen J. McPherson, Joseph J. Bianco, Gerald R. Cunha, Yuzhuo Wang, and Gail P. Risbridger

Prostatic hormonal carcinogenesis is mediated by in situ estrogen production and estrogen receptor alpha signaling
FASEB J. 2008 22: 1512-1520. [Abstract] [Full Text] [PDF]  

Béatrice Benayoun, Stephen Baghdiguian, Alicia Lajmanovich, Marc Bartoli, Nathalie Daniele, Evelyne Gicquel, Nathalie Bourg, Fabrice Raynaud, Marie-Anne Pasquier, Laurence Suel, Hanns Lochmuller, Gérard Lefranc, and Isabelle Richard

NF-B-dependent expression of the antiapoptotic factor c-FLIP is regulated by calpain 3, the protein involved in limb-girdle muscular dystrophy type 2A
FASEB J. 2008 22: 1521-1529. [Abstract] [Full Text] [PDF]  

Lars Jakobsson, Anna Domogatskaya, Karl Tryggvason, David Edgar, and Lena Claesson-Welsh

Laminin deposition is dispensable for vasculogenesis but regulates blood vessel diameter independent of flow
FASEB J. 2008 22: 1530-1539. [Abstract] [Full Text] [PDF] Supplemental Data  

Michael Mederos y Schnitzler, Janine Wäring, Thomas Gudermann, and Vladimir Chubanov

Evolutionary determinants of divergent calcium selectivity of TRPM channels
FASEB J. 2008 22: 1540-1551. [Abstract] [Full Text] [PDF] Supplemental Data  

Ritchie Williamson, Alessia Usardi, Diane P. Hanger, and Brian H. Anderton

Membrane-bound β-amyloid oligomers are recruited into lipid rafts by a fyn-dependent mechanism
FASEB J. 2008 22: 1552-1559. [Abstract] [Full Text] [PDF] Supplemental Data  

Adriano Spreafico, Silvia Schenone, Tommaso Serchi, Maurizio Orlandini, Adriano Angelucci, David Magrini, Giulia Bernardini, Giulia Collodel, Anna Di Stefano, Cristina Tintori, Mauro Bologna, Fabrizio Manetti, Maurizio Botta, and Annalisa Santucci

Antiproliferative and proapoptotic activities of new pyrazolo[3,4-d]pyrimidine derivative Src kinase inhibitors in human osteosarcoma cells
FASEB J. 2008 22: 1560-1571. [Abstract] [Full Text] [PDF] Supplemental Data  

Barry I. Hudson, Angela M. Carter, Evis Harja, Anastasia Z. Kalea, Maria Arriero, Hojin Yang, Peter J. Grant, and Ann Marie Schmidt

Identification, classification, and expression of RAGE gene splice variants
FASEB J. 2008 22: 1572-1580. [Abstract] [Full Text] [PDF]  

Enrique Syriani, Azucena Gomez-Cabrero, Marta Bosch, Alicia Moya, Elena Abad, Arcadi Gual, Xavier Gasull, and Miguel Morales

Profilin induces lamellipodia by growth factor-independent mechanism
FASEB J. 2008 22: 1581-1596. [Abstract] [Full Text] [PDF] Supplemental Data  

Y. Greenberg, M. King, W. B. Kiosses, K. Ewalt, X. Yang, P. Schimmel, J. S. Reader, and E. Tzima

The novel fragment of tyrosyl tRNA synthetase, mini-TyrRS, is secreted to induce an angiogenic response in endothelial cells
FASEB J. 2008 22: 1597-1605. [Abstract] [Full Text] [PDF]  

Guo-Rui Dou, Yao-Chun Wang, Xing-Bin Hu, Li-Hong Hou, Chun-Mei Wang, Jian-Feng Xu, Yu-Sheng Wang, Ying-Min Liang, Li-Bo Yao, An-Gang Yang, and Hua Han

RBP-J, the transcription factor downstream of Notch receptors, is essential for the maintenance of vascular homeostasis in adult mice
FASEB J. 2008 22: 1606-1617. [Abstract] [Full Text] [PDF] Supplemental Data  

Erratum:

Erratum
FASEB J. 2008 22: 1618. [Full Text] [PDF]  

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