Editorial:

Coalition of Scientific Societies

Evolution and Its Discontents: A Role for Scientists in Science Education
FASEB J. 2008 22: 1-4. [Full Text] [PDF] Supplemental Data  

Research Communications:

Claire Pecqueur, Thi Bui, Chantal Gelly, Julie Hauchard, Céline Barbot, Frederic Bouillaud, Daniel Ricquier, Bruno Miroux, and Craig B. Thompson

Uncoupling protein-2 controls proliferation by promoting fatty acid oxidation and limiting glycolysis-derived pyruvate utilization
FASEB J. 2008 22: 9-18. [Abstract] [Full Text] [PDF]  

Jeffrey F. Breit, Katheryn Ault-Ziel, Abu-Bakr Al-Mehdi, and Mark N. Gillespie

Nuclear protein-induced bending and flexing of the hypoxic response element of the rat vascular endothelial growth factor promoter
FASEB J. 2008 22: 19-29. [Abstract] [Full Text] [PDF]  

Mark Kirsch, Barbara Kemp-Harper, Norbert Weissmann, Friedrich Grimminger, and Harald H. H. W. Schmidt

Sildenafil in hypoxic pulmonary hypertension potentiates a compensatory up-regulation of NO-cGMP signaling
FASEB J. 2008 22: 30-40. [Abstract] [Full Text] [PDF]  

Shlomit Gorelik, Moshe Ligumsky, Ron Kohen, and Joseph Kanner

A novel function of red wine polyphenols in humans: prevention of absorption of cytotoxic lipid peroxidation products
FASEB J. 2008 22: 41-46. [Abstract] [Full Text] [PDF]  

Yan Zhou, Anitha Suram, Chitra Venugopal, Annamalai Prakasam, Suizhen Lin, Yuan Su, Baolin Li, Steven M. Paul, and Kumar Sambamurti

Geranylgeranyl pyrophosphate stimulates -secretase to increase the generation of Aβ and APP-CTF
FASEB J. 2008 22: 47-54. [Abstract] [Full Text] [PDF]  

Tatiana V. Kramarova, Irina G. Shabalina, Ulf Andersson, Rolf Westerberg, Inger Carlberg, Josef Houstek, Jan Nedergaard, and Barbara Cannon

Mitochondrial ATP synthase levels in brown adipose tissue are governed by the c-Fo subunit P1 isoform
FASEB J. 2008 22: 55-63. [Abstract] [Full Text] [PDF]  

Volker Endeward, Jean-Pierre Cartron, Pierre Ripoche, and Gerolf Gros

RhAG protein of the Rhesus complex is a CO₂ channel in the human red cell membrane
FASEB J. 2008 22: 64-73. [Abstract] [Full Text] [PDF]  

Shin-ichi Yokota, Tamaki Okabayashi, Noriko Yokosawa, and Nobuhiro Fujii

Measles virus P protein suppresses Toll-like receptor signal through up-regulation of ubiquitin-modifying enzyme A20
FASEB J. 2008 22: 74-83. [Abstract] [Full Text] [PDF]  

Ilka Pinz, Jeffrey Robbins, Namakkal S. Rajasekaran, Ivor J. Benjamin, and Joanne S. Ingwall

Unmasking different mechanical and energetic roles for the small heat shock proteins CryAB and HSPB2 using genetically modified mouse hearts
FASEB J. 2008 22: 84-92. [Abstract] [Full Text] [PDF] Supplemental Data  

Cherkaouia Kibaly, Laurence Meyer, Christine Patte-Mensah, and Ayikoe G. Mensah-Nyagan

Biochemical and functional evidence for the control of pain mechanisms by dehydroepiandrosterone endogenously synthesized in the spinal cord
FASEB J. 2008 22: 93-104. [Abstract] [Full Text] [PDF]  

Mark Band, Imad Shams, Alma Joel, and Aaron Avivi

Cloning and in vivo expression of vascular endothelial growth factor receptor 2 (Flk1) in the naturally hypoxia-tolerant subterranean mole rat
FASEB J. 2008 22: 105-112. [Abstract] [Full Text] [PDF]  

Hong Seok Choi, Bong Seok Kang, Jung-Hyun Shim, Yong-Yeon Cho, Bu Young Choi, Ann M. Bode, and Zigang Dong

Cot, a novel kinase of histone H3, induces cellular transformation through up-regulation of c-fos transcriptional activity
FASEB J. 2008 22: 113-126. [Abstract] [Full Text] [PDF]  

Zheng Xu, Levina Suk Mi Lam, Lok Hei Lam, So Fun Chau, Tzi Bun Ng, and Shannon Wing Ngor Au

Molecular basis of the redox regulation of SUMO proteases: a protective mechanism of intermolecular disulfide linkage against irreversible sulfhydryl oxidation
FASEB J. 2008 22: 127-137. [Abstract] [Full Text] [PDF]  

Yanqiu Deng, Bin Li, Fei Liu, Khalid Iqbal, Inge Grundke-Iqbal, Roland Brandt, and Cheng-Xin Gong

Regulation between O-GlcNAcylation and phosphorylation of neurofilament-M and their dysregulation in Alzheimer disease
FASEB J. 2008 22: 138-145. [Abstract] [Full Text] [PDF] Supplemental Data  

Jörg Piontek, Lars Winkler, Hartwig Wolburg, Sebastian L. Müller, Nikolaj Zuleger, Christian Piehl, Burkhard Wiesner, Gerd Krause, and Ingolf E. Blasig

Formation of tight junction: determinants of homophilic interaction between classic claudins
FASEB J. 2008 22: 146-158. [Abstract] [Full Text] [PDF] Supplemental Data  

Gino V. Limmon, Mohamed Arredouani, Kelly L. McCann, Radiah A. Corn Minor, Lester Kobzik, and Farhad Imani

Scavenger receptor class-A is a novel cell surface receptor for double-stranded RNA
FASEB J. 2008 22: 159-167. [Abstract] [Full Text] [PDF]  

Tamar Shultz, Miriam Shmuel, Tehila Hyman, and Yoram Altschuler

β-tubulin cofactor D and ARL2 take part in apical junctional complex disassembly and abrogate epithelial structure
FASEB J. 2008 22: 168-182. [Abstract] [Full Text] [PDF] Supplemental Data  

Youssef H. Zeidan, Bill X. Wu, Russell W. Jenkins, Lina M. Obeid, and Yusuf A. Hannun

A novel role for protein kinase C-mediated phosphorylation of acid sphingomyelinase in UV light-induced mitochondrial injury
FASEB J. 2008 22: 183-193. [Abstract] [Full Text] [PDF]  

Benoit R. Gauthier, Dominique L. Duhamel, Mariella Iezzi, Sten Theander, Frédéric Saltel, Mitsunori Fukuda, Bernhard Wehrle-Haller, and Claes B. Wollheim

Synaptotagmin VII splice variants , β, and are expressed in pancreatic β-cells and regulate insulin exocytosis
FASEB J. 2008 22: 194-206. [Abstract] [Full Text] [PDF]  

Daniel Sher, Yelena Fishman, Naomi Melamed-Book, Mingliang Zhang, and Eliahu Zlotkin

Osmotically driven prey disintegration in the gastrovascular cavity of the green hydra by a pore-forming protein
FASEB J. 2008 22: 207-214. [Abstract] [Full Text] [PDF] Supplemental Data  

Stefan Schildknecht, Andreas Daiber, Sandro Ghisla, Richard A. Cohen, and Markus M. Bachschmid

Acetaminophen inhibits prostanoid synthesis by scavenging the PGHS-activator peroxynitrite
FASEB J. 2008 22: 215-224. [Abstract] [Full Text] [PDF] Supplemental Data  

Martin F. Crook, Michelle Olive, Hai-Hui Xue, Thomas H. Langenickel, Manfred Boehm, Warren J. Leonard, and Elizabeth G. Nabel

GA-binding protein regulates KIS gene expression, cell migration, and cell cycle progression
FASEB J. 2008 22: 225-235. [Abstract] [Full Text] [PDF]  

Na Chen and Joseph L. Napoli

All-trans-retinoic acid stimulates translation and induces spine formation in hippocampal neurons through a membrane-associated RAR
FASEB J. 2008 22: 236-245. [Abstract] [Full Text] [PDF]  

Wei-Qin Zhao, Fernanda G. De Felice, Sara Fernandez, Hui Chen, Mary P. Lambert, Michael J. Quon, Grant A. Krafft, and William L. Klein

Amyloid beta oligomers induce impairment of neuronal insulin receptors
FASEB J. 2008 22: 246-260. [Abstract] [Full Text] [PDF]  

Yuan-Hao Chen, Brandon K. Harvey, Alexander F. Hoffman, Yun Wang, Yung-Hsiao Chiang, and Carl R. Lupica

MPTP-induced deficits in striatal synaptic plasticity are prevented by glial cell line-derived neurotrophic factor expressed via an adeno-associated viral vector
FASEB J. 2008 22: 261-275. [Abstract] [Full Text] [PDF]  

Mazin Magzoub, Songwan Jin, and A. S. Verkman

Enhanced macromolecule diffusion deep in tumors after enzymatic digestion of extracellular matrix collagen and its associated proteoglycan decorin
FASEB J. 2008 22: 276-284. [Abstract] [Full Text] [PDF] Supplemental Data  

Joseph Tam, Victoria Trembovler, Vincenzo Di Marzo, Stefania Petrosino, Gabriella Leo, Alex Alexandrovich, Eran Regev, Nardy Casap, Arie Shteyer, Catherine Ledent, Meliha Karsak, Andreas Zimmer, Raphael Mechoulam, Raz Yirmiya, Esther Shohami, and Itai Bab

The cannabinoid CB1 receptor regulates bone formation by modulating adrenergic signaling
FASEB J. 2008 22: 285-294. [Abstract] [Full Text] [PDF]  

Stefano Franceschini, Andrea Ilari, Daniela Verzili, Carlotta Zamparelli, Anaid Antaramian, Angélica Rueda, Hector H. Valdivia, Emilia Chiancone, and Gianni Colotti

Molecular basis for the impaired function of the natural F112L sorcin mutant: X-ray crystal structure, calcium affinity, and interaction with annexin VII and the ryanodine receptor
FASEB J. 2008 22: 295-306. [Abstract] [Full Text] [PDF]  

Maria L. Allende, Dapeng Zhou, Danielle N. Kalkofen, Sonia Benhamed, Galina Tuymetova, Christine Borowski, Albert Bendelac, and Richard L. Proia

S1P₁ receptor expression regulates emergence of NKT cells in peripheral tissues
FASEB J. 2008 22: 307-315. [Abstract] [Full Text] [PDF]  

José María Eirín-López, Toyotaka Ishibashi, and Juan Ausió

H2A.Bbd: a quickly evolving hypervariable mammalian histone that destabilizes nucleosomes in an acetylation-independent way
FASEB J. 2008 22: 316-326. [Abstract] [Full Text] [PDF] Supplemental Data  

Letters to the Editor:

Pierre Mormède, Marie-Pierre Moisan, and Wim E. Crusio

Does a polymorphic glucocorticoid receptor explain inherited altered stress response and increased anxiety-type behaviors in a mouse population?
FASEB J. 2008 22: 5-6. [Full Text] [PDF]  

You Zhou, Sasha Zheng, Whitney Sprout, Jennifer McDonald, and Merlyn K. Nielsen

Additional evidence showing an additive effect of glucocorticoid receptor polymorphisms on anxiety-type behavior, stress response, and body weight in a population of mice with low heat loss background
FASEB J. 2008 22: 6-8. [Full Text] [PDF]  

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