Editorial:

Gerald Weissmann

Swift-boating Darwin: alternative or complementary science
FASEB J. 2006 20: 405-407. [Full Text] [PDF]  

Essay:

Frederick Grinnell

Intelligent design: fallacy recapitulates ontogeny
FASEB J. 2006 20: 410-411. [Full Text] [PDF]  

FASEB Statement:

FASEB opposes using science classes to teach intelligent design, creationism, and other non-scientific beliefs
FASEB J. 2006 20: 408-409. [Full Text] [PDF]  

Research Communications:

Omar M. A. El-Agnaf, Sultan A. Salem, Katerina E. Paleologou, Martin D. Curran, Mark J. Gibson, Jennifer A. Court, Michael G. Schlossmacher, and David Allsop

Detection of oligomeric forms of -synuclein protein in human plasma as a potential biomarker for Parkinson’s disease
FASEB J. 2006 20: 419-425. [Abstract] [Full Text] [PDF]  

Dara L. Dickstein, Kaan E. Biron, Maki Ujiie, Cheryl G. Pfeifer, Andrew R. Jeffries, and Wilfred A. Jefferies

Aß peptide immunization restores blood-brain barrier integrity in Alzheimer disease
FASEB J. 2006 20: 426-433. [Abstract] [Full Text] [PDF]  

Daniel Lindén, Lena William-Olsson, Andrea Ahnmark, Kim Ekroos, Carina Hallberg, Helena P. Sjögren, Bruno Becker, Lennart Svensson, John C. Clapham, Jan Oscarsson, and Sandra Schreyer

Liver-directed overexpression of mitochondrial glycerol-3-phosphate acyltransferase results in hepatic steatosis, increased triacylglycerol secretion and reduced fatty acid oxidation
FASEB J. 2006 20: 434-443. [Abstract] [Full Text] [PDF] Supplemental Data  

Martin Roderfeld, Ralf Weiskirchen, Sandra Wagner, Marie-Luise Berres, Corinna Henkel, Joachim Grötzinger, Axel M. Gressner, Siegfried Matern, and Elke Roeb

Inhibition of hepatic fibrogenesis by matrix metalloproteinase-9 mutants in mice
FASEB J. 2006 20: 444-454. [Abstract] [Full Text] [PDF]  

Kyung S. Lee, Ho K. Lee, Joel S. Hayflick, Yong C. Lee, and Kamal D. Puri

Inhibition of phosphoinositide 3-kinase attenuates allergic airway inflammation and hyperresponsiveness in murine asthma model
FASEB J. 2006 20: 455-465. [Abstract] [Full Text] [PDF]  

Anna S. Hui, Amy L. Bauer, Justin B. Striet, Phillip O. Schnell, and Maria F. Czyzyk-Krzeska

Calcium signaling stimulates translation of HIF- during hypoxia
FASEB J. 2006 20: 466-475. [Abstract] [Full Text] [PDF]  

FJ Express Summaries:

Irma G. Gonzalez-Herrera, Leonel Prado-Lourenco, Frédéric Pileur, Caroline Conte, Aurélie Morin, Florence Cabon, Hervé Prats, Stephan Vagner, Francis Bayard, Sylvie Audigier, and Anne-Catherine Prats

Testosterone regulates FGF-2 expression during testis maturation by an IRES-dependent translational mechanism
FASEB J. 2006 20: 476-478. [Full Text] [PDF]  

Jun Yu, Li Lei, Yuxin Liang, Linda Hinh, Reed P. Hickey, Yan Huang, Dinggang Liu, Jennifer L. Yeh, Edward Rebar, Casey Case, Kaye Spratt, William C. Sessa, and Frank J. Giordano

An engineered VEGF-activating zinc finger protein transcription factor improves blood flow and limb salvage in advanced-age mice
FASEB J. 2006 20: 479-481. [Full Text] [PDF]  

Tarek A. Taha, Kazuyuki Kitatani, Mazen El-Alwani, Jacek Bielawski, Yusuf A. Hannun, and Lina M. Obeid

Loss of sphingosine kinase-1 activates the intrinsic pathway of programmed cell death: modulation of sphingolipid levels and the induction of apoptosis
FASEB J. 2006 20: 482-484. [Full Text] [PDF]  

Svitlana Garbuzova-Davis, Sylvia J. Gografe, Cyndy Davis Sanberg, Alison E. Willing, Samuel Saporta, Don F. Cameron, Tammy Desjarlais, Jennifer Daily, Nicole Kuzmin-Nichols, Wilfredo Chamizo, Stephen K. Klasko, and Paul R. Sanberg

Maternal transplantation of human umbilical cord blood cells provides prenatal therapy in Sanfilippo type B mouse model
FASEB J. 2006 20: 485-487. [Full Text] [PDF]  

Laura L. Schulz and Jessica K. Tyler

The histone chaperone ASF1 localizes to active DNA replication forks to mediate efficient DNA replication
FASEB J. 2006 20: 488-490. [Full Text] [PDF]  

Ana Mingorance, Marta Solé, Vilma Munetón, Albert Martínez, Manuel Nieto-Sampedro, Eduardo Soriano, and José Antonio del Río

Regeneration of lesioned entorhino-hippocampal axons in vitro by combined degradation of inhibitory proteoglycans and blockade of Nogo-66/NgR signaling
FASEB J. 2006 20: 491-493. [Full Text] [PDF]  

William Même, Charles-Félix Calvo, Nicolas Froger, Pascal Ezan, Edwige Amigou, Annette Koulakoff, and Christian Giaume

Proinflammatory cytokines released from microglia inhibit gap junctions in astrocytes: potentiation by ß-amyloid
FASEB J. 2006 20: 494-496. [Full Text] [PDF]  

Fang C. Mei, Travis W. Young, Jinsong Liu, and Xiaodong Cheng

RAS-mediated epigenetic inactivation of OPCML in oncogenic transformation of human ovarian surface epithelial cells
FASEB J. 2006 20: 497-499. [Full Text] [PDF]  

Christine Goffinet and Oliver T. Keppler

Efficient nonviral gene delivery into primary lymphocytes from rats and mice
FASEB J. 2006 20: 500-502. [Full Text] [PDF]  

Loïc Lemonnier, Mohamed Trebak, Jean-Philippe Lievremont, Gary S. Bird, and James W. Putney, Jr.

Protection of TRPC7 cation channels from calcium inhibition by closely associated SERCA pumps
FASEB J. 2006 20: 503-505. [Full Text] [PDF]  

Melinda C. Myzak, W. Mohaiza Dashwood, Gayle A. Orner, Emily Ho, and Roderick H. Dashwood

Sulforaphane inhibits histone deacetylase in vivo and suppresses tumorigenesis in Apc^min mice
FASEB J. 2006 20: 506-508. [Full Text] [PDF]  

Catherine M. Waters, Jaclyn Long, Irina Gorshkova, Yuko Fujiwara, Michelle Connell, Kristen E. Belmonte, Gabor Tigyi, Viswanathan Natarajan, Susan Pyne, and Nigel J. Pyne

Cell migration activated by platelet-derived growth factor receptor is blocked by an inverse agonist of the sphingosine 1-phosphate receptor-1
FASEB J. 2006 20: 509-511. [Full Text] [PDF]  

Elzbieta Kojro, Rolf Postina, Corinna Buro, Christoph Meiringer, Katja Gehrig-Burger, and Falk Fahrenholz

The neuropeptide PACAP promotes the -secretase pathway for processing the Alzheimer amyloid precursor protein
FASEB J. 2006 20: 512-514. [Full Text] [PDF]  

David M. Thomas, Dina M. Francescutti-Verbeem, and Donald M. Kuhn

Gene expression profile of activated microglia under conditions associated with dopamine neuronal damage
FASEB J. 2006 20: 515-517. [Full Text] [PDF] Supplemental Data  

Nicolas Clavreul, Takeshi Adachi, David R. Pimental, Yasuo Ido, Christian Schöneich, and Richard A. Cohen

S-glutathiolation by peroxynitrite of p21ras at cysteine-118 mediates its direct activation and downstream signaling in endothelial cells
FASEB J. 2006 20: 518-520. [Full Text] [PDF] Supplemental Data  

R. A. Billington, E. A. Bellomo, E. M. Floriddia, J. Erriquez, C. Distasi, and A. A. Genazzani

A transport mechanism for NAADP in a rat basophilic cell line
FASEB J. 2006 20: 521-523. [Full Text] [PDF]  

Melanie Gerard, Zeger Debyser, Linda Desender, Philipp J. Kahle, Johan Baert, Veerle Baekelandt, and Yves Engelborghs

The aggregation of alpha-synuclein is stimulated by FK506 binding proteins as shown by fluorescence correlation spectroscopy
FASEB J. 2006 20: 524-526. [Full Text] [PDF]  

Adriana Albini, Raffaella Dell’Eva, Roberta Vené, Nicoletta Ferrari, Donald R. Buhler, Douglas M. Noonan, and Gianfranco Fassina

Mechanisms of the antiangiogenic activity by the hop flavonoid xanthohumol: NF-B and Akt as targets
FASEB J. 2006 20: 527-529. [Full Text] [PDF]  

Roman V. Kondratov, Rashmi K. Shamanna, Anna A. Kondratova, Victoria Y. Gorbacheva, and Marina P. Antoch

Dual role of the CLOCK/BMAL1 circadian complex in transcriptional regulation
FASEB J. 2006 20: 530-532. [Full Text] [PDF]  

Ken-ichiro Inoue, Hirohisa Takano, Akinori Shimada, Emiko Wada, Rie Yanagisawa, Miho Sakurai, Masahiko Satoh, and Toshikazu Yoshikawa

Role of metallothionein in coagulatory disturbance and systemic inflammation induced by lipopolysaccharide in mice
FASEB J. 2006 20: 533-535. [Full Text] [PDF]  

Liming Jin, Tongyun Liu, Gwen A. Lagoda, Hunter C. Champion, Trinity J. Bivalacqua, and Arthur L. Burnett

Elevated RhoA/Rho-kinase activity in the aged rat penis: mechanism for age-associated erectile dysfunction
FASEB J. 2006 20: 536-538. [Full Text] [PDF]  

Liming Jin, Clare E. Foss, Xueying Zhao, Thomas M. Mills, Mong-Heng Wang, Lynnette P. McCluskey, Ganesh S. S. Yaddanapud, John R. Falck, John D. Imig, and R. Clinton Webb

Cytochrome P450 epoxygenases provide a novel mechanism for penile erection
FASEB J. 2006 20: 539-541. [Full Text] [PDF]  

Timothy D. Warner, Ivana Vojnovic, David Bishop-Bailey, and Jane A. Mitchell

Influence of plasma protein on the potencies of inhibitors of cyclooxygenase-1 and -2
FASEB J. 2006 20: 542-544. [Full Text] [PDF]  

Karl Kunzelmann, Kerstin Scheidt, Birgit Scharf, Jiraporn Ousingsawat, Rainer Schreiber, Brandon Wainwright, and Brendan McMorran

Flagellin of Pseudomonas aeruginosa inhibits Na⁺ transport in airway epithelia
FASEB J. 2006 20: 545-546. [Full Text] [PDF]  

Asya Rolls, Liora Cahalon, Sharon Bakalash, Hila Avidan, Ofer Lider, and Michal Schwartz

A sulfated disaccharide derived from chondroitin sulfate proteoglycan protects against inflammation-associated neurodegeneration
FASEB J. 2006 20: 547-549. [Full Text] [PDF]  

Silvia C. Matsumoto, Vivian Labovsky, Marcela Roncoroni, María C. Guida, Luisa Giménez, Jorge Mitelman, Horacio Gori, Renata Jurgelevicius, Alejandro Grillo, Pablo Manfredi, Mariano J. Levin, and Cristina Paveto

Retinal dysfunction in patients with chronic Chagas’ disease is associated to anti-Trypanosoma cruzi antibodies that cross-react with rhodopsin
FASEB J. 2006 20: 550-552. [Full Text] [PDF]  

Guangdong Yang, Lingyun Wu, and Rui Wang

Pro-apoptotic effect of endogenous H₂S on human aorta smooth muscle cells
FASEB J. 2006 20: 553-555. [Full Text] [PDF]  

Iqbal Sayeed, Suhel Parvez, Kirstin Winkler-Stuck, Gordon Seitz, Isabelle Trieu, Claus-Werner Wallesch, Peter Schönfeld, and Detlef Siemen

Patch clamp reveals powerful blockade of the mitochondrial permeability transition pore by the D2-receptor agonist pramipexole
FASEB J. 2006 20: 556-558. [Full Text] [PDF]  

Sotirios N. Sotiriou, Valeria V. Orlova, Nadia Al-Fakhri, Eveliina Ihanus, Matina Economopoulou, Berend Isermann, Khalil Bdeir, Peter P. Nawroth, Klaus T. Preissner, Carl G. Gahmberg, Marlys L. Koschinsky, and Triantafyllos Chavakis

Lipoprotein(a) in atherosclerotic plaques recruits inflammatory cells through interaction with Mac-1 integrin
FASEB J. 2006 20: 559-561. [Full Text] [PDF]  

Serena Fineschi, Walter Reith, Pierre André Guerne, Jean-Michel Dayer, and Carlo Chizzolini

Proteasome blockade exerts an antifibrotic activity by coordinately down-regulating type I collagen and tissue inhibitor of metalloproteinase-1 and up-regulating metalloproteinase-1 production in human dermal fibroblasts
FASEB J. 2006 20: 562-564. [Full Text] [PDF]  

K. R. Knight, Y. Uda, M. W. Findlay, D. L. Brown, K. J. Cronin, E. Jamieson, T. Tai, E. Keramidaris, A. J. Penington, J. Rophael, L. C. Harrison, and W. A. Morrison

Vascularized tissue-engineered chambers promote survival and function of transplanted islets and improve glycemic control
FASEB J. 2006 20: 565-567. [Full Text] [PDF]  

Giuseppe D’Argenio, Marta Valenti, Giuseppe Scaglione, Vittorio Cosenza, Italo Sorrentini, and Vincenzo Di Marzo

Up-regulation of anandamide levels as an endogenous mechanism and a pharmacological strategy to limit colon inflammation
FASEB J. 2006 20: 568-570. [Full Text] [PDF]  

Ikuko Miyazaki, Masato Asanuma, Francisco J. Diaz-Corrales, Masaya Fukuda, Kiyoyuki Kitaichi, Ko Miyoshi, and Norio Ogawa

Methamphetamine-induced dopaminergic neurotoxicity is regulated by quinone formation-related molecules
FASEB J. 2006 20: 571-573. [Full Text] [PDF]  

Ulrich Warskulat, Elena Borsch, Roland Reinehr, Birgit Heller-Stilb, Irmhild Mönnighoff, Darius Buchczyk, Markus Donner, Ulrich Flögel, Günther Kappert, Sibylle Soboll, Sandra Beer, Klaus Pfeffer, Hanns-Ulrich Marschall, Marcus Gabrielsen, Mahmood Amiry-Moghaddam, Ole Petter Ottersen, Hans Peter Dienes, and Dieter Häussinger

Chronic liver disease is triggered by taurine transporter knockout in the mouse
FASEB J. 2006 20: 574-576. [Full Text] [PDF]  

Ioannis Charalampopoulos, Vassilia-Ismini Alexaki, Iakovos Lazaridis, Erene Dermitzaki, Nicolaos Avlonitis, Christos Tsatsanis, Theodora Calogeropoulou, Andrew N. Margioris, Elias Castanas, and Achille Gravanis

G protein-associated, specific membrane binding sites mediate the neuroprotective effect of dehydroepiandrosterone
FASEB J. 2006 20: 577-579. [Full Text] [PDF]  

Carissa A. Steelman, Justin C. Recknor, Dan Nettleton, and James M. Reecy

Transcriptional profiling of myostatin-knockout mice implicates Wnt signaling in postnatal skeletal muscle growth and hypertrophy
FASEB J. 2006 20: 580-582. [Full Text] [PDF] Supplemental Data  

Bertrand Léger, Lodovica Vergani, Gianni Sorarù, Peter Hespel, Wim Derave, Charles Gobelet, Carla D'Ascenzio, Corrado Angelini, and Aaron P. Russell

Human skeletal muscle atrophy in amyotrophic lateral sclerosis reveals a reduction in Akt and an increase in atrogin-1
FASEB J. 2006 20: 583-585. [Full Text] [PDF]  

Life Sciences Forum:

Chiara Laezza, Maria Notarnicola, Maria Gabriella Caruso, Caterina Messa, Marco Macchia, Simone Bertini, Filippo Minutolo, Giuseppe Portella, Laura Fiorentino, Stefania Stingo, and Maurizio Bifulco

N6-isopentenyladenosine arrests tumor cell proliferation by inhibiting farnesyl diphosphate synthase and protein prenylation
FASEB J. 2006 20: 412-418. [Abstract] [Full Text] [PDF]  

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