FASEB J. Cell Migration Consortium
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Chambon, P.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Chambon, P.

The FASEB Journal, Vol 10, 940-954, Copyright © 1996 by The Federation of American Societies for Experimental Biology

REVIEWS

A decade of molecular biology of retinoic acid receptors

P Chambon
Institut de Genetique et de Biologie Moleculaire et Cellulaire, CNRS/INSERUM/ULP, College de France, Strasbourg, France.

Retinoids play an important role in development, differentiation, and homeostasis. The discovery of retinoid receptors belonging to the superfamily of nuclear ligand-activated transcriptional regulators has revolutionized our molecular understanding as to how these structurally simple molecules exert their pleiotropic effects. Diversity in the control of gene expression by retinoid signals is generated through complexity at different levels of the signaling pathway. A major source of diversity originates from the existence of two families of retinoid acid (RA) receptors (R), the RAR isotypes (alpha, beta, and gamma) and the three RXR isotypes (alpha, beta, and gamma), and their numerous isoforms, which bind as RXR/RAR heterodimers to the polymorphic cis- acting response elements of RA target genes. The possibility of cross- modulation (cross-talk) with cell-surface receptors signaling pathways, as well as the finding that RARs and RXRs interact with multiple putative coactivators and/or corepressors, generates additional levels of complexity for the array of combinatorial effects that underlie the pleiotropic effects of retinoids. This review focuses on recent developments, particularly in the area of structure-function relationships.


This article has been cited by other articles:


Home page
 J. Nutr.Home page
P. V. Bhat and D.-C. Manolescu
Role of Vitamin A in Determining Nephron Mass and Possible Relationship to Hypertension
J. Nutr., August 1, 2008; 138(8): 1407 - 1410.
[Abstract] [Full Text] [PDF]

Home page
 J. Nutr.Home page
D. E. Lackey, S. L. Ashley, A. L. Davis, and K. A. Hoag
Retinoic Acid Decreases Adherence of Murine Myeloid Dendritic Cells and Increases Production of Matrix Metalloproteinase-9
J. Nutr., August 1, 2008; 138(8): 1512 - 1519.
[Abstract] [Full Text] [PDF]

Home page
 Proc. Natl. Acad. Sci. USAHome page
S. M. Nowickyj, J. V. Chithalen, D. Cameron, M. G. Tyshenko, M. Petkovich, G. R. Wyatt, G. Jones, and V. K. Walker
Locust retinoid X receptors: 9-Cis-retinoic acid in embryos from a primitive insect
PNAS, July 15, 2008; 105(28): 9540 - 9545.
[Abstract] [Full Text] [PDF]

Home page
 Clin. Cancer Res.Home page
H. Tatebe, M. Shimizu, Y. Shirakami, H. Tsurumi, and H. Moriwaki
Synergistic Growth Inhibition by 9-cis-Retinoic Acid Plus Trastuzumab in Human Hepatocellular Carcinoma Cells
Clin. Cancer Res., May 1, 2008; 14(9): 2806 - 2812.
[Abstract] [Full Text] [PDF]

Home page
 Physiol. GenomicsHome page
J. Chen, S. A. Carney, R. E. Peterson, and W. Heideman
Comparative genomics identifies genes mediating cardiotoxicity in the embryonic zebrafish heart
Physiol Genomics, April 21, 2008; 33(2): 148 - 158.
[Abstract] [Full Text] [PDF]

Home page
 Mol. Cell. Biol.Home page
Z. Vucetic, Z. Zhang, J. Zhao, F. Wang, K. J. Soprano, and D. R. Soprano
Acinus-S' Represses Retinoic Acid Receptor (RAR)-Regulated Gene Expression through Interaction with the B Domains of RARs
Mol. Cell. Biol., April 15, 2008; 28(8): 2549 - 2558.
[Abstract] [Full Text] [PDF]

Home page
 EndocrinologyHome page
G. Zappala, C. Elbi, J. Edwards, J. Gorenstein, M. M. Rechler, and N. Bhattacharyya
Induction of Apoptosis in Human Prostate Cancer Cells by Insulin-Like Growth Factor Binding Protein-3 Does Not Require Binding to Retinoid X Receptor-{alpha}
Endocrinology, April 1, 2008; 149(4): 1802 - 1812.
[Abstract] [Full Text] [PDF]

Home page
 Mol. Cell. Biol.Home page
S. McNamara, H. Wang, N. Hanna, and W. H. Miller Jr.
Topoisomerase II{beta} Negatively Modulates Retinoic Acid Receptor {alpha} Function: a Novel Mechanism of Retinoic Acid Resistance
Mol. Cell. Biol., March 15, 2008; 28(6): 2066 - 2077.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Respir. Cell Mol. Bio.Home page
A. Druilhe, J.-M. Zahm, L. Benayoun, D. El Mehdi, M. Grandsaigne, M.-C. Dombret, I. Mosnier, B. Feger, J. Depondt, M. Aubier, et al.
Epithelium Expression and Function of Retinoid Receptors in Asthma
Am. J. Respir. Cell Mol. Biol., March 1, 2008; 38(3): 276 - 282.
[Abstract] [Full Text] [PDF]

Home page
 Reproductive SciencesHome page
G. Chaudhuri
Nuclear Receptors and Female Reproduction: A Tale of 3 Scientists, Jensen, Gustafsson, and O'Malley
Reproductive Sciences, February 1, 2008; 15(2): 110 - 120.
[Abstract] [PDF]

Home page
 Am. J. Physiol. Heart Circ. Physiol.Home page
R. Choudhary, A. Palm-Leis, R. C. Scott III, R. S. Guleria, E. Rachut, K. M. Baker, and J. Pan
All-trans retinoic acid prevents development of cardiac remodeling in aortic banded rats by inhibiting the renin-angiotensin system
Am J Physiol Heart Circ Physiol, February 1, 2008; 294(2): H633 - H644.
[Abstract] [Full Text] [PDF]

Home page
 J. Immunol.Home page
X. Chen, B. L. Esplin, K. P. Garrett, R. S. Welner, C. F. Webb, and P. W. Kincade
Retinoids Accelerate B Lineage Lymphoid Differentiation
J. Immunol., January 1, 2008; 180(1): 138 - 145.
[Abstract] [Full Text] [PDF]

Home page
 Ann. N. Y. Acad. Sci.Home page
T. J. DOYLE, K. W. BRAUN, D. J. MCLEAN, R. W. WRIGHT, M. D. GRISWOLD, and K. H. KIM
Potential Functions of Retinoic Acid Receptor A in Sertoli Cells and Germ Cells During Spermatogenesis
Ann. N.Y. Acad. Sci., December 1, 2007; 1120(1): 114 - 130.
[Abstract] [Full Text] [PDF]

Home page
 Arch NeurolHome page
M. Tafti and N. B. Ghyselinck
Functional Implication of the Vitamin A Signaling Pathway in the Brain
Arch Neurol, December 1, 2007; 64(12): 1706 - 1711.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Gastrointest. Liver Physiol.Home page
E. Grenier, F. S. Maupas, J.-F. Beaulieu, E. Seidman, E. Delvin, A. Sane, E. Tremblay, C. Garofalo, and E. Levy
Effect of retinoic acid on cell proliferation and differentiation as well as on lipid synthesis, lipoprotein secretion, and apolipoprotein biogenesis
Am J Physiol Gastrointest Liver Physiol, December 1, 2007; 293(6): G1178 - G1189.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
S. Hessel, A. Eichinger, A. Isken, J. Amengual, S. Hunzelmann, U. Hoeller, V. Elste, W. Hunziker, R. Goralczyk, V. Oberhauser, et al.
CMO1 Deficiency Abolishes Vitamin A Production from beta-Carotene and Alters Lipid Metabolism in Mice
J. Biol. Chem., November 16, 2007; 282(46): 33553 - 33561.
[Abstract] [Full Text] [PDF]

Home page
 J. Leukoc. Biol.Home page
K. Kim, H. H. Kim, J. H. Kim, Y. H. Choi, Y. H. Kim, and J. Cheong
Chemokine stromal cell-derived factor-1 induction by C/EBP{beta} activation is associated with all-trans-retinoic acid-induced leukemic cell differentiation
J. Leukoc. Biol., November 1, 2007; 82(5): 1332 - 1339.
[Abstract] [Full Text] [PDF]

Home page
 J. Clin. Endocrinol. Metab.Home page
I. Aeberli, R. Biebinger, R. Lehmann, D. l'Allemand, G. A. Spinas, and M. B. Zimmermann
Serum Retinol-Binding Protein 4 Concentration and Its Ratio to Serum Retinol Are Associated with Obesity and Metabolic Syndrome Components in Children
J. Clin. Endocrinol. Metab., November 1, 2007; 92(11): 4359 - 4365.
[Abstract] [Full Text] [PDF]

Home page
 Arch Otolaryngol Head Neck SurgHome page
K. Chen, R. Sawhney, M. Khan, M. S. Benninger, Z. Hou, S. Sethi, J. K. Stephen, and M. J. Worsham
Methylation of Multiple Genes as Diagnostic and Therapeutic Markers in Primary Head and Neck Squamous Cell Carcinoma
Arch Otolaryngol Head Neck Surg, November 1, 2007; 133(11): 1131 - 1138.
[Abstract] [Full Text] [PDF]

Home page
 GutHome page
K. Yamazaki, M. Shimizu, M. Okuno, R. Matsushima-Nishiwaki, N. Kanemura, H. Araki, H. Tsurumi, S. Kojima, I B. Weinstein, and H. Moriwaki
Synergistic effects of RXR{alpha} and PPAR{gamma} ligands to inhibit growth in human colon cancer cells phosphorylated RXR{alpha} is a critical target for colon cancer management
Gut, November 1, 2007; 56(11): 1557 - 1563.
[Abstract] [Full Text] [PDF]

Home page
 Stem CellsHome page
B. Coleman, M. G. de Silva, and R. K. Shepherd
Concise Review: The Potential of Stem Cells for Auditory Neuron Generation and Replacement
Stem Cells, November 1, 2007; 25(11): 2685 - 2694.
[Abstract] [Full Text] [PDF]

Home page
 EndocrinologyHome page
W. S. Blaner and C. L. Mendelsohn
Retinoid Inactivation: Survival Factor for Male Germ Cells
Endocrinology, October 1, 2007; 148(10): 4557 - 4559.
[Full Text] [PDF]

Home page
 EndocrinologyHome page
G. MacLean, H. Li, D. Metzger, P. Chambon, and M. Petkovich
Apoptotic Extinction of Germ Cells in Testes of Cyp26b1 Knockout Mice
Endocrinology, October 1, 2007; 148(10): 4560 - 4567.
[Abstract] [Full Text] [PDF]

Home page
 DevelopmentHome page
J. Bowles and P. Koopman
Retinoic acid, meiosis and germ cell fate in mammals
Development, October 1, 2007; 134(19): 3401 - 3411.
[Abstract] [Full Text] [PDF]

Home page
 Stem CellsHome page
P. Luo, A. Wang, K. J. Payne, H. Peng, J.-g. Wang, Y. K. Parrish, J. W. Rogerio, T. J. Triche, Q. He, and L. Wu
Intrinsic Retinoic Acid Receptor {alpha}-Cyclin-Dependent Kinase-Activating Kinase Signaling Involves Coordination of the Restricted Proliferation and Granulocytic Differentiation of Human Hematopoietic Stem Cells
Stem Cells, October 1, 2007; 25(10): 2628 - 2637.
[Abstract] [Full Text] [PDF]

Home page
 J. Immunol.Home page
S. G. Kang, H. W. Lim, O. M. Andrisani, H. E. Broxmeyer, and C. H. Kim
Vitamin A Metabolites Induce Gut-Homing FoxP3+ Regulatory T Cells
J. Immunol., September 15, 2007; 179(6): 3724 - 3733.
[Abstract] [Full Text] [PDF]

Home page
 Biol. Reprod.Home page
E. J Su, Y.-H. Cheng, R. T Chatterton, Z.-H. Lin, P. Yin, S. Reierstad, J. Innes, and S. E Bulun
Regulation of 17-Beta Hydroxysteroid Dehydrogenase Type 2 in Human Placental Endothelial Cells
Biol Reprod, September 1, 2007; 77(3): 517 - 525.
[Abstract] [Full Text] [PDF]

Home page
 Clin. Cancer Res.Home page
N. Chakravarti, R. Lotan, A. H. Diwan, C. L. Warneke, M. M. Johnson, and V. G. Prieto
Decreased Expression of Retinoid Receptors in Melanoma: Entailment in Tumorigenesis and Prognosis
Clin. Cancer Res., August 15, 2007; 13(16): 4817 - 4824.
[Abstract] [Full Text] [PDF]

Home page
 DevelopmentHome page
F. Chen, T. J. Desai, J. Qian, K. Niederreither, J. Lu, and W. V. Cardoso
Inhibition of Tgf{beta} signaling by endogenous retinoic acid is essential for primary lung bud induction
Development, August 15, 2007; 134(16): 2969 - 2979.
[Abstract] [Full Text] [PDF]

Home page
 Hum ReprodHome page
J. D. Wren, Y. Wu, and S.-W. Guo
A system-wide analysis of differentially expressed genes in ectopic and eutopic endometrium
Hum. Reprod., August 1, 2007; 22(8): 2093 - 2102.
[Abstract] [Full Text] [PDF]

Home page
 DevelopmentHome page
F. M. J. Jacobs, S. M. Smits, C. W. Noorlander, L. von Oerthel, A. J. A. van der Linden, J. P. H. Burbach, and M. P. Smidt
Retinoic acid counteracts developmental defects in the substantia nigra caused by Pitx3 deficiency
Development, July 15, 2007; 134(14): 2673 - 2684.
[Abstract] [Full Text] [PDF]

Home page
 BloodHome page
H. Hattori, X. Zhang, Y. Jia, K. K. Subramanian, H. Jo, F. Loison, P. E. Newburger, and H. R. Luo
RNAi screen identifies UBE2D3 as a mediator of all-trans retinoic acid-induced cell growth arrest in human acute promyelocytic NB4 cells
Blood, July 15, 2007; 110(2): 640 - 650.
[Abstract] [Full Text] [PDF]

Home page
 J. Clin. Endocrinol. Metab.Home page
P. G. McTernan and S. Kumar
Retinol Binding Protein 4 and Pathogenesis of Diabetes
J. Clin. Endocrinol. Metab., July 1, 2007; 92(7): 2430 - 2432.
[Full Text] [PDF]

Home page
 Exp. Biol. Med.Home page
M. Wagner and M. A. Q. Siddiqui
Signal Transduction in Early Heart Development (II): Ventricular Chamber Specification, Trabeculation, and Heart Valve Formation
Experimental Biology and Medicine, July 1, 2007; 232(7): 866 - 880.
[Abstract] [Full Text] [PDF]

Home page
 Cancer Res.Home page
A. L. Anding, J. S. Chapman, D. W. Barnett, R. W. Curley Jr., and M. Clagett-Dame
The Unhydrolyzable Fenretinide Analogue 4-Hydroxybenzylretinone Induces the Proapoptotic Genes GADD153 (CHOP) and Bcl-2-Binding Component 3 (PUMA) and Apoptosis that Is Caspase- Dependent and Independent of the Retinoic Acid Receptor
Cancer Res., July 1, 2007; 67(13): 6270 - 6277.
[Abstract] [Full Text] [PDF]

Home page
 Arterioscler. Thromb. Vasc. Bio.Home page
N. Kada, T. Suzuki, K. Aizawa, T. Matsumura, N. Ishibashi, N. Suzuki, N. Takeda, Y. Munemasa, D. Sawaki, T. Ishikawa, et al.
Acyclic Retinoid Inhibits Neointima Formation Through Retinoic Acid Receptor Beta-Induced Apoptosis
Arterioscler. Thromb. Vasc. Biol., July 1, 2007; 27(7): 1535 - 1541.
[Abstract] [Full Text] [PDF]

Home page
 J. Immunol.Home page
F. Zapata-Gonzalez, F. Rueda, J. Petriz, P. Domingo, F. Villarroya, A. de Madariaga, and J. C. Domingo
9-cis-Retinoic Acid (9cRA), a Retinoid X Receptor (RXR) Ligand, Exerts Immunosuppressive Effects on Dendritic Cells by RXR-Dependent Activation: Inhibition of Peroxisome Proliferator-Activated Receptor {gamma} Blocks Some of the 9cRA Activities, and Precludes Them to Mature Phenotype Development
J. Immunol., May 15, 2007; 178(10): 6130 - 6139.
[Abstract] [Full Text] [PDF]

Home page
 Diabetes CareHome page
N. Stefan, A. M. Hennige, H. Staiger, J. Machann, F. Schick, E. Schleicher, A. Fritsche, and H.-U. Haring
High Circulating Retinol-Binding Protein 4 Is Associated With Elevated Liver Fat but Not With Total, Subcutaneous, Visceral, or Intramyocellular Fat in Humans
Diabetes Care, May 1, 2007; 30(5): 1173 - 1178.
[Abstract] [Full Text] [PDF]

Home page
 BloodHome page
L. A. Moraes, K. E. Swales, J. A. Wray, A. Damazo, J. M. Gibbins, T. D. Warner, and D. Bishop-Bailey
Nongenomic signaling of the retinoid X receptor through binding and inhibiting Gq in human platelets
Blood, May 1, 2007; 109(9): 3741 - 3744.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
K. Saavalainen, M. I. Tammi, T. Bowen, M. L. Schmitz, and C. Carlberg
Integration of the Activation of the Human Hyaluronan Synthase 2 Gene Promoter by Common Cofactors of the Transcription Factors Retinoic Acid Receptor and Nuclear Factor {kappa}B
J. Biol. Chem., April 13, 2007; 282(15): 11530 - 11539.
[Abstract] [Full Text] [PDF]

Home page
 Nucleic Acids ResHome page
P. Gupta, S. W. Park, M. Farooqui, and L.-N. Wei
Orphan nuclear receptor TR2, a mediator of preadipocyte proliferation, is differentially regulated by RA through exchange of coactivator PCAF with corepressor RIP140 on a platform molecule GRIP1
Nucleic Acids Res., April 1, 2007; 35(7): 2269 - 2282.
[Abstract] [Full Text] [PDF]

Home page
 Mol. Cell. ProteomicsHome page
M. D. M. Huq, N.-P. Tsai, S. A. Khan, and L.-N. Wei
Lysine Trimethylation of Retinoic Acid Receptor-{alpha}: A Novel Means To Regulate Receptor Function
Mol. Cell. Proteomics, April 1, 2007; 6(4): 677 - 688.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Endocrinol. Metab.Home page
R. Zaragoza, A. Gimeno, V. J. Miralles, E. R. Garcia-Trevijano, R. Carmena, C. Garcia, M. Mata, I. R. Puertes, L. Torres, and J. R. Vina
Retinoids induce MMP-9 expression through RAR{alpha} during mammary gland remodeling
Am J Physiol Endocrinol Metab, April 1, 2007; 292(4): E1140 - E1148.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
R. J. Jones, S. Dickerson, P. M. Bhende, H.-J. Delecluse, and S. C. Kenney
Epstein-Barr Virus Lytic Infection Induces Retinoic Acid-responsive Genes through Induction of a Retinol-metabolizing Enzyme, DHRS9
J. Biol. Chem., March 16, 2007; 282(11): 8317 - 8324.
[Abstract] [Full Text] [PDF]

Home page
 J EndocrinolHome page
K. Han, H. Song, I. Moon, R. Augustin, K. Moley, M. Rogers, and H. Lim
Utilization of DR1 as true RARE in regulating the Ssm, a novel retinoic acid-target gene in the mouse testis
J. Endocrinol., March 1, 2007; 192(3): 539 - 551.
[Abstract] [Full Text] [PDF]

Home page
 Cancer Res.Home page
J. Huang, Z. D. Liang, T.-T. Wu, A. Hoque, H. Chen, Y. Jiang, H. Zhang, and X.-c. Xu
Tumor-Suppressive Effect of Retinoid Receptor-Induced Gene-1 (RRIG1) in Esophageal Cancer
Cancer Res., February 15, 2007; 67(4): 1589 - 1593.
[Abstract] [Full Text] [PDF]

Home page
 Clin. Cancer Res.Home page
C. A. Righini, F. de Fraipont, J.-F. Timsit, C. Faure, E. Brambilla, E. Reyt, and M.-C. Favrot
Tumor-Specific Methylation in Saliva: A Promising Biomarker for Early Detection of Head and Neck Cancer Recurrence
Clin. Cancer Res., February 15, 2007; 13(4): 1179 - 1185.
[Abstract] [Full Text] [PDF]

Home page
 Cancer Res.Home page
K. Ohnuma-Ishikawa, T. Morio, T. Yamada, Y. Sugawara, M. Ono, M. Nagasawa, A. Yasuda, C. Morimoto, K. Ohnuma, N. H. Dang, et al.
Knockdown of XAB2 Enhances All-Trans Retinoic Acid-Induced Cellular Differentiation in All-Trans Retinoic Acid-Sensitive and -Resistant Cancer Cells
Cancer Res., February 1, 2007; 67(3): 1019 - 1029.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
A. R. Moise, M. Golczak, Y. Imanishi, and K. Palczewski
Topology and Membrane Association of Lecithin: Retinol Acyltransferase
J. Biol. Chem., January 19, 2007; 282(3): 2081 - 2090.
[Abstract] [Full Text] [PDF]

Home page
 Cancer Res.Home page
L. J. Donato, J. H. Suh, and N. Noy
Suppression of Mammary Carcinoma Cell Growth by Retinoic Acid: the Cell Cycle Control Gene Btg2 Is a Direct Target for Retinoic Acid Receptor Signaling
Cancer Res., January 15, 2007; 67(2): 609 - 615.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
A. Isken, J. Holzschuh, J. M. Lampert, L. Fischer, V. Oberhauser, K. Palczewski, and J. von Lintig
Sequestration of Retinyl Esters Is Essential for Retinoid Signaling in the Zebrafish Embryo
J. Biol. Chem., January 12, 2007; 282(2): 1144 - 1151.
[Abstract] [Full Text] [PDF]

Home page
 Mol. Endocrinol.Home page
O. Ziouzenkova, G. Orasanu, G. Sukhova, E. Lau, J. P. Berger, G. Tang, N. I. Krinsky, G. G. Dolnikowski, and J. Plutzky
Asymmetric Cleavage of {beta}-Carotene Yields a Transcriptional Repressor of Retinoid X Receptor and Peroxisome Proliferator-Activated Receptor Responses
Mol. Endocrinol., January 1, 2007; 21(1): 77 - 88.
[Abstract] [Full Text] [PDF]

Home page
 Mol. Endocrinol.Home page
S. Folkertsma, P. I. van Noort, A. de Heer, P. Carati, R. Brandt, A. Visser, G. Vriend, and J. de Vlieg
The Use of in Vitro Peptide Binding Profiles and in Silico Ligand-Receptor Interaction Profiles to Describe Ligand-Induced Conformations of the Retinoid X Receptor {alpha} Ligand-Binding Domain
Mol. Endocrinol., January 1, 2007; 21(1): 30 - 48.
[Abstract] [Full Text] [PDF]

Home page
 J. Lipid Res.Home page
X.-H. Tang, M.-J. Suh, R. Li, and L. J. Gudas
Cell proliferation inhibition and alterations in retinol esterification induced by phytanic acid and docosahexaenoic acid
J. Lipid Res., January 1, 2007; 48(1): 165 - 176.
[Abstract] [Full Text] [PDF]

Home page
 Molecular Cancer TherapeuticsHome page
Y. Kato, B. C. Salumbides, X.-F. Wang, D. Z. Qian, S. Williams, Y. Wei, T. B. Sanni, P. Atadja, and R. Pili
Antitumor effect of the histone deacetylase inhibitor LAQ824 in combination with 13-cis-retinoic acid in human malignant melanoma
Mol. Cancer Ther., January 1, 2007; 6(1): 70 - 81.
[Abstract] [Full Text] [PDF]

Home page
 J. Nutr.Home page
C. W. Xiao, J. Mei, W. Huang, C. Wood, M. R. L'Abbe, G. S. Gilani, G. M. Cooke, and I. H. Curran
Dietary Soy Protein Isolate Modifies Hepatic Retinoic Acid Receptor-{beta} Proteins and Inhibits Their DNA Binding Activity in Rats
J. Nutr., January 1, 2007; 137(1): 1 - 6.
[Abstract] [Full Text] [PDF]

Home page
 Clin. Cancer Res.Home page
M. D. Williams, N. Chakravarti, M. S. Kies, S.-I. Maruya, J. N. Myers, J. C. Haviland, R. S. Weber, R. Lotan, and A. K. El-Naggar
Implications of Methylation Patterns of Cancer Genes in Salivary Gland Tumors
Clin. Cancer Res., December 15, 2006; 12(24): 7353 - 7358.
[Abstract] [Full Text] [PDF]

Home page
 Pharmacol. Rev.Home page
P. Germain, B. Staels, C. Dacquet, M. Spedding, and V. Laudet
Overview of Nomenclature of Nuclear Receptors
Pharmacol. Rev., December 1, 2006; 58(4): 685 - 704.
[Abstract] [Full Text] [PDF]

Home page
 Pharmacol. Rev.Home page
P. Germain, P. Chambon, G. Eichele, R. M. Evans, M. A. Lazar, M. Leid, A. R. De Lera, R. Lotan, D. J. Mangelsdorf, and H. Gronemeyer
International Union of Pharmacology. LX. Retinoic Acid Receptors
Pharmacol. Rev., December 1, 2006; 58(4): 712 - 725.
[Abstract] [Full Text] [PDF]

Home page
 Pharmacol. Rev.Home page
P. Germain, P. Chambon, G. Eichele, R. M. Evans, M. A. Lazar, M. Leid, A. R. De Lera, R. Lotan, D. J. Mangelsdorf, and H. Gronemeyer
International Union of Pharmacology. LXIII. Retinoid X Receptors
Pharmacol. Rev., December 1, 2006; 58(4): 760 - 772.
[Abstract] [Full Text] [PDF]

Home page