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This Article Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Alert me to new issues of the journal Download to citation manager Google Scholar Articles by Teo, C. C. Articles by Sabaté, J. PubMed Articles by Teo, C. C. Articles by Sabaté, J.

Effect on blood pressure of diets enriched with different sources of n-3 fatty acids in healthy adults

¹ Department of Nutrition
² Department of Epidemiology and Biostatistics, Loma Linda University, Loma Linda, CA

ABSTRACT

Background: Consumption of n-3 fatty acids from algal-oil supplements and plant sources produce health benefits, which may be dependent on the reduction in blood pressure.

Aim and Methods: To determine if plant sources (flaxseed oil and walnuts) of á-linolenic acid (ALA) produce similar change in blood pressure (BP) as algal-oil (EPA/DHA) supplements, we performed a randomized 4x3 cross-over study (4 diets and 3 8-week study periods) in 24 healthy adults (15 women, 9 men; mean±SE age 42±2.7 years; BMI 25.4±0.9 kg/m2). Under controlled feeding conditions, subjects consumed eucaloric lacto-ovo vegetarian diets: Control, ALA (6-7g/2400 kcal/d), EPA/DHA (0.20/0.72g EPA/DHA per 2400 kcal/d), and, Combination (ALA + EPA/DHA). Under controlled conditions, 6 BP readings, (3/day on 2 days) were taken at the beginning and end of each diet period.

Results: Significant (p < 0.001) reduction in systolic BP were observed in all four diets: Control (-2.64%), EPA/DHA (-2.42%), ALA (-1.64%) and Combination (-1.85%) while non-significant (p > 0.05) reduction were observed in the diastolic BP: Control (-2.03%), EPA/DHA (-2.51%), ALA (-0.05%) and no change for the Combination diets (0.0%). No significant differences in BP between diets were observed.

Conclusion: Following diets enriched with ALA, EPA/DHA or a combination of these fatty acids for 8 weeks do not seem to affect BP when compared with the control diet.

This Article Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Alert me to new issues of the journal Download to citation manager Google Scholar Articles by Teo, C. C. Articles by Sabaté, J. PubMed Articles by Teo, C. C. Articles by Sabaté, J.