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(The FASEB Journal. 2007;21:lb247)
© 2007 FASEB
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lb247

EFFECTS OF NUTRITION SUPPLEMENTS IN HEAVY SMOKERS

Fabrizia Bamonti1, Cristina Novembrino1, Roberto Accinni2, Cinzia Della Noce2, Dario Gregori3, Silvia Lonati1 and Gianfranco Schiraldi4

1 Dpt Scienze Mediche, Università degli Studi, Osp. Maggiore Policlinico, Mangiagalli e Regina Elena, Fond IRCCS, via F. Sforza, 35, Milan, Italy,
2 Ist Fisiologia Clinica, CNR, Osp Niguarda Ca’ Granda, Piazza Ospedale Maggiore, 3, Milan, Italy,
3 Dpt Public Health, University of Torino, via Santana, 5, Turin, Italy,
4 Dpt Pneumologia, Osp Niguarda Ca’ Granda, Piazza Ospedale Maggiore, 3, Milan, Italy

ABSTRACT

Cigarette smoking can have a negative effect on markers of health and nutrition status, which supplementation may attenuate. We evaluated potential beneficial effects of supplementation with two different encapsulated formulas, consisting primarily of mixed juice powder concentrate, on spirometry (pulmonary function), and concentrations of folate and total homocysteine (tHcy). Sixty-one heavy smokers (>20 cigarettes/d, duration ≥10y, age 40–60y, 35 male) were randomized into three groups: A-placebo; B-fruit/vegetable; and, C-fruit/vegetable/berry. Median values were compared at baseline (T0) and after three months supplementation (T1).


Table 1

Diffusing lung capacity, measured by carbon monoxide transfer factor (TLCO), improved in groups B and C. Serum and erythrocyte folate significantly increased in both B and C, while tHcy significantly decreased. These data show improvements with both experimental formulas compared to placebo.

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This Article
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