Improved lung growth and function through hypoxia-inducible factor in primate chronic lung disease of prematurity FASEB J. Asikainen et al.
20: 1698
Supplemental Data
Files in this Data Supplement:
Supplemental Data -
(SupplementalData.pdf; 983 KB) Supplemental Figure 1: Assessment of lung pressure-volume curve in FG-4095 treated preterm baboons relative to untreated controls. Supplemental Figure 2: Hemodynamic evaluation of preterm baboons with and without FG-4095 treatment. Supplemental Figure 3: ARNT expression in cells treated with PHD-inhibitors in vitro. Supplemental Table 1: Criteria for baboon exclusion. Supplemental Table 2: Necropsy blood chemistry variables in control and FG-4095 treated baboons. Supplemental Table 3: Pharmacologic blood pressure support in preterm baboons (125+14 d pro re nata O2). Supplemental Table 4: Evaluation of pneumonitis and microscopic and gross bleeding in control and FG-4095 treated baboons.