Supplemental Data

Files in this Data Supplement:

• Supplemental Data - (SupplementalData.pdf; 2.31 MB)

  Supplemental Figure 1: Survivin is overexpressed in CRC, and contains an active Crm1-dependent nuclear export signal.
  Supplemental Figure 2: The Survivin-Crm1 interaction is dependent on Ran-GTP in GST-pulldown-assays.
  Supplemental Figure 3: Survivin-NES antibodies (NES-Ab) are specific and inhibit nuclear export of survivin.
  Table S1: Tumor stages and clinical characteristics of CRC patients examined by microarray (A) and qPCR (B) analysis.
  Table S2: Tumor stages and clinical characteristics of HNSCC patients examined by RT-qPCR analysis.
  Table S3: Overall clinical characteristics of CRC patients examined by IHC.