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Figure 1. Fold-change of VEGF-A, thrombospondin-1 (TSP-1), and connective tissue growth factor (CTGF) mRNA content in trained healthy (diagonally striped bars), sedentary diabetic (black bars) and trained diabetic (horizontally striped bars) mouse calf muscles compared to the sedentary healthy controls (white bars, set to value 1). Values are mean ± SE. *P < 0.05 vs. healthy sedentary controls,
P < 0.05 vs. respective sedentary diabetic (=effect of training). Note the varying scale on the Y-axis due to the magnitude and direction of the changes.