FASEB J.
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Figure 1


Figure 1. Effect of s.c. AngII infusion (1.1 mg/kg/day for 2 wk) on WT and Nox2–/– mice. A) Myocardial NADPH oxidase activity measured by 5 µM lucigenin-enhanced chemiluminescence. B) Interstitial fibrosis assessed by image analysis of Masson’s Trichrome stained sections. C–F) Messenger RNA transcripts assessed by real-time RT-PCR (data are normalized by GAPDH mRNA and expressed as arbitrary units [AU]). *P < 0.05.





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