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Figure 2. Evolution of Le expression of H. pylori strain J166 in four rhesus monkeys of different Le phenotypes. Lex and Ley expression of strain J166 preinoculation was determined in eight single colony-derived cell populations. At 40 wk, the Le phenotype of the strains recovered from the two Lea–b+ animals [C (82A49), D (8PZ)] showed predominance of Ley expression (bottom). In contrast, in the two Lea+b– animals [A (E6C), B (85D08)] at 40 wk, the predominant Le expression of the J166 populations had shifted from Ley to Lex.
