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Figure 1. Zebrafish igf1ra and igf1rb play overlapping but nonredundant roles in regulating growth and developmental rate. A) Morphology of 24 hpf embryos injected with igf1ra MOs, igf1rb MOs, igf1ra MOs + igf1rb MOs (igf1rab MO), or control MOs. Scale bar = 250 µm. B) Body length and C) somite number of embryos shown in panel A. Results are from 3 independent experiments, each with 15 embryos per group. *P < 0.0001 compared with the control MO-injected group, and #P < 0.001 compared with that of the igf1ra or igf1rb MO-injected group.
