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Figure 1. Effect of rosiglitazone (RSG) and ruboxistaurin (RBX) on (A) EB dye permeability and (B) total water content in epididymal fat. Zucker lean (LEAN) and fatty (FATTY) rats were treated with regular chow (CTL) and RSG (RSG) for 4 weeks and then studied. A separate group of rats was treated with RSG for 2 wk and another 2 wk with chow containing RSG and RBX. N = number of rats studied. Values plotted are mean ± SEM.
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