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Figure 2. Schematic overview. Ca2+ oscillations induced by HlyA occur only in the presence of the toxin and are not blocked by nifedipine. After washout of HlyA, Ca2+ oscillations cease rapidly. Readdition of the toxin again leads to Ca2+ oscillations. We assume that the decrease after a Ca2+ elevation is managed by plasma membrane and sarco/endoplasmic reticulum Ca2+ pumps (illustrated by circles with blades).
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