FASEB J.
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Figure 2


Figure 2. Proposed mechanism for the regulation of allergic inflammation via protease-mediated cleavage of allergens. A) Resting effector cells of allergic patients contain Fc{epsilon}RI-bound allergen-specific IgE. B) Allergens cross-link and aggregate effector cell-bound IgE antibodies. C) Proteases released in the course of allergic inflammation cleave allergens. D) Termination of allergic degranulation occurs.





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