Click on image to view larger version.
Figure 1. Histological findings and pressure-volume relations.
Representative Masson Trichrom stainings of hearts (top) in relation to in vivo measured pressure-volume relations (bottom) of same mice 30 days after MI. Sham (A), infarcted and G-CSF-treated (B), and infarcted and saline-treated mice (C). Sham-operated mice revealed normal pressure-volume relations with low end systolic and end diastolic volumes (A), whereas infarcted animals revealed low LV pressures with high filling volumes resulting in a lower ejection fraction (C), which was partially restored in G-CSF treated animals resulting in a shift to the left of the PV loops (B).
