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Figure 3. Schematic Diagram.
A) In the syngeneic transplantation setting, BM Scal+ cells derived from GFP transgenic mice were injected into CFP transgenic recipients. The cells generated by differentiation express GFP, but no CFP. The cells generated by fusion express both GFP and CFP. B) In the Xenogeneic transplantation setting, human CB HSCs were injected into NOD/SCID/IL2rgnull mice. The cells generated by differentiation possess human chromosomes, but not murine chromosomes. The cells generated by fusion possess both human and murine chromosomes.
