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Figure 1. The effects of thiazolidinediones on hepatocellular proliferation following partial hepatectomy. (A) Hepatocellular BrdU immunohistochemistry and histology (hematoxylin and eosin staining, H&E) of liver harvested 36 h after partial hepatectomy from vehicle- (Veh), troglitazone- (Tro), pioglitazone- (Pio), and rosiglitazone- (Rosi) treated mice (50-µm scale bar is shown in the upper left panel). (B) Summary of hepatocellular proliferation 36 h after partial hepatectomy (*P <0.02 for vehicle vs. rosiglitazone). (C) Summary of hepatocellular proliferation at serial times after partial hepatectomy. (*P <0.04 for vehicle vs. pioglitazone or rosiglitazone; **P <0.02 for vehicle vs. rosiglitazone).
