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Figure 1. Small, intermediate, and large channel nAChR current amplitudes present in a single inside-out patch activated by 30 µM levamisole. A) Single-channel openings from single patch recording at + 75 mV, showing examples of 3 separate channel currents: O1, O2, and O3 are the open levels, and C is closed level. B) Current amplitude histogram of patch recording best fitted by sum of 3 Gaussian distributions: peaks are 2.12 ± 1.47, 2.84 ± 0.05, and 3.83 ± 0.01 pA (mean±SE) and have conductances of 26, 36, and 48 pS .
