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Figure 2. Preconditioning inhibits late and dramatic mitochondrial membrane depolarization and cell death in PDK1^fl/+, but not PDK1^fl/–, mice. A) Original images of preconditioned PDK1^fl/+ and PDK1^fl/– cardiomyocytes loaded with JC-1 exposed to hypoxia. Horizontal white bar represents 30 µm. B) Time course corresponding to (A).

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