FASEB J.
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Table 1. Number of up-regulated gene transcripts at 2 and 24 h

B7-DC Xab induction time Unique probes Probes displaying 2-fold difference from matched controls (probability of 2-fold variation by chance) Composite probability Expected and observed events
Sample 1 Sample 2 Sample 3 Probability of any given probe being 2-fold different from control in all 3 samples Expected frequency of probes on chip displaying 2-fold differences by chance Number of probes observed displaying 2-fold differences Identified unique genes represented among identified probes
2 h 22,576 1695 2189 1656 4.61 x 10–4 10.4 461 229
(up-regulated) (0.075) (0.084) (0.073)
2 h 22,679 2164 1844 2321 7.94 x 10–4 18.0 207 89
(down-regulated) (0.095) (0.081) (0.10)
24 h 22,597 1726 2400 1893 6.80 x 10–4 15.3 461 232
(up-regulated) (0.076) (0.106) (0.084)
24 h 22,645 2394 1593 2152 7.07 x 10–4 16.0 539 196
(down-regulated) (0.106) (0.070) (0.095)





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