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Figure 3. Schematic diagram. The nanoTiO2-induced genes in different pathways according to the KEGG pathway database and BIOCARTA. The pink color indicates nanoTiO2-induced genes, the red numbers close to the genes the fold increase. A) The cell cycle and apoptosis pathways. B) The PlGF/chemokines pathway and the classic complement pathway. The hypothetical nanoTiO2-regulated signaling pathways were modified from the KEGG and BIOCARTA database, while the PlGF pathway was modified from Selvaraj SK, 2003.