|
|
||||||||
|
Figure 2. Schematic diagram of the experimental findings. As glycosylated ECD
2 binds to IL-13 with high affinity, it effectively blocks IL-13-induced STAT6 phosphorylation, cell proliferation, protein synthesis, and IL-13 cytotoxin-induced cytotoxicity. N-linked glycosylation is critical for optimal inhibitory effect as deglycosylated ECD
2 demonstrated little effect on IL-13-induced STAT6 phosphorylation.
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |