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Figure 1. COX-2/ primary neurons are more vulnerable to camptothecin-induced DNA damage and cell death. Cells were treated with serum-free medium supplemented with camptothecin (5 µM) for 16 h. The number of healthy intact nuclei was evaluated by phase microscopy. The results are mean ± SE of 3 separate experiments. Significant at *P < 0.05; **P < 0.01.
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