Click on image to view larger version.
Figure 1. Ladostigil regulated Bcl-2 family proteins: Bcl-2, Bax, and Bad. SK-N-SH cells were maintained in fibrous sheath (FS) for 1 or 5 d and acute-treated without (cont.) or with increasing concentrations of ladostigil. Bcl-2, Bax (A) and Bad (C) levels were examined by immunoblot analysis. The loading of the lanes was normalized to levels of ß-Actin. B) Ratios of Bcl-2/Bax protein levels. Densitometric analysis of Western blot obtained from three independent experiments, and data are expressed as mean ± SEM; *P < 0.01, **P < 0.001 vs. control.
