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Figure 1. LV remodeling after MI. A) Development of LV dilatation at the papillary level under baseline conditions and over 8 wk after MI in p50 KO and WT animals. KO animals had significantly less LV dilatation and preserved LV function compared to WTs (ESD end-systolic diameter, EDD end-diastolic diameter, FS fractional shortening; *P 
0.05, **P 0.01, KO MI vs. WT MI, 
P 0.05, P 0.001 sham vs. MI). B) Representative M-modes at the papillary level of a sham operated or an infarcted WT and KO animal 56 days after MI (PW: posterior wall, IVS interventricular septum).
