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Figure 1. EEG analyses in OP-exposed group individuals show decreased power in the theta and increased power in the beta bands in specific brain regions: A) Average normalized power spectrum (1.5–30 Hz) of exposed (n =19) and non-exposed (n =9) groups. B) Area under the curve (AUC) of average normalized power by discrete frequency bands (delta: 1.5–6 Hz, theta: 6.5–8 Hz, alpha1: 8.5–10 Hz, alpha2: 10.5–12 Hz, beta1: 12.5–18 Hz, beta2: 18.5–21 Hz, beta3: 21.5–30 Hz) in exposed and non-exposed groups. In the exposed group, theta activity was significantly decreased (P =0.04) and beta3 activity was significantly increased (P =0.03). C, D) Percentage of increase in a normalized spectral power at the theta and beta3 bands is shown as a spectral power distribution map. Note the electrode-specific changes of spectral power. E, F) LORETA analyses showing cortical regions with statistically significant differences between exposed and non-exposed groups. E) Areas with significantly decreased current intensity (blue, P <0.05) in the theta band included bilaterally the amygdala, the hippocampus, the subcallosal area, the parahippocampal gyrus, and the anterior and posterior cingulate gyrus (Brodmann Areas 25, 30, 31, 34, 36, 37). F) Areas with significantly decreased (blue, P <0.05) current density in the beta 3 band included the hippocampus and parahippocampal gyrus bilaterally; increased sources (red, P <0.05) were found in the inferior, middle, and superior frontal gyri (areas 10, 11, 27, 46).
