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Figure 3. Expression patterns in PDGF-B–/– embryos. The severe reduction in the density of pericytes in PDGF-B–/– brain correlates with the loss of RGS5 expression seen in PDGFB–/– mice, confirming the pericyte-specific expression of RGS5 in the brain (A, B). This loss of expression can also be seen with Kir6.1, DLK, and SUR2B (D, F, H), further implicating their pericyte-specific expression. The microvessels are still present (arrowheads) and occasional in situ positive pericytes are seen (B, arrow).
