Supplemental Data

Files in this Data Supplement:

• Figure S1 - AQP1 expression in the choroid plexus. A) Sagittal section of a mouse brain. The boxed area is shown schematically in (C). B) AQP1 positive cellc counts per 100 µm² (± stdev) (P>0.25). In both cases, no significant changes were observed between wt and TgS animals. C) Schematic illustration of the choroids plexus. The boxed area is shown in (D). D) AQP1 immunohistochemistry. [Rabbit anti-AQP1 antibody (Chemicon, AB3065, 5 µg/ml) was detected using fluorescein-tagged anti-rabbit antibody (Jackson ImmunoResearch, 1:250)]. (pdf, 1 MB)
• Table S1 - Listed are the 213 genes expressed in the prefrontal cortex (PFC) which showed over 2-fold higher expression levels in TgS transgenic mice overexpressing synaptic acetylcholinesterase, AChE-S as compared with strain-matched FVB/N controls. The color codes mark G proteins (purple); Transcription-associated genes (pink); Channels (yellow); Adhesion-related genes (grey); Glutamate receptors (turquoise), Actin/cytoskeleton genes (green); and Kinases/phosphatases (white). Symbols and subclassifications follow the GOC database. See text for details. (xls, 113 KB)
• Table S2 - Overexpressed terms in the TgS PFC. Classification of categories follows the GOC database. See text for details. (xls, 576 KB)