| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
|
|
|
|||||||
|
|||||||||
The FASEB Journal, Vol 9, 509-515, Copyright © 1995 by The Federation of American Societies for Experimental Biology
REVIEWS |
MA Valverde, SP Hardy and FV Sepulveda
Nuffield Department of Clinical Biochemistry, John Radcliffe Hospital, University of Oxford, United Kingdom.
Chloride channels play important functions in different aspects of cell physiology including volume regulation, transepithelial ion transport and stabilization of membrane potential. In recent years the molecular identity of the chloride channels defective in cystic fibrosis and myotonia congenita has been elucidated, highlighting the importance of anion-selective channels in cell and tissue function. Concurrently, several proteins have been identified as chloride channels along with proteins that possess channel regulatory behavior. Novel interactions with more potent pharmacological compounds have been reported with different chloride channels. This burgeoning field of interest is reviewed.
This article has been cited by other articles:
|
|
 |
|
  H. Li, W. Wen, L. Cheng, J. Shi, H. Jiang, Y. Oh, and G. Xu Expression of Chloride Channel Protein CLC-3 in Patients With Allergic Rhinitis: Effect of Topical Corticosteroid Treatment Arch Otolaryngol Head Neck Surg, March 1, 2008; 134(3): 301 - 305. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. M. Fernandez-Fernandez, M. Nobles, A. Currid, E. Vazquez, and M. A. Valverde Maxi K+ channel mediates regulatory volume decrease response in a human bronchial epithelial cell line Am J Physiol Cell Physiol, December 1, 2002; 283(6): C1705 - C1714. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 S. Dupre-Aucouturier, A. Penhoat, O. Rougier, and A. Bilbaut ACTH-induced Cl- current in bovine adrenocortical cells: correlation with cortisol secretion Am J Physiol Endocrinol Metab, February 1, 2002; 282(2): E355 - E365. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. I. Niemeyer, L. P. Cid, L. F. Barros, and F. V. Sepulveda Modulation of the Two-pore Domain Acid-sensitive K+ Channel TASK-2 (KCNK5) by Changes in Cell Volume J. Biol. Chem., November 9, 2001; 276(46): 43166 - 43174. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 L. Al-Nakkash and P. S. Reinach Activation of a CFTR-Mediated Chloride Current in a Rabbit Corneal Epithelial Cell Line Invest. Ophthalmol. Vis. Sci., September 1, 2001; 42(10): 2364 - 2370. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
L. P. Cid, M.-I. Niemeyer, A. Ramirez, and F. V. Sepulveda Splice variants of a ClC-2 chloride channel with differing functional characteristics Am J Physiol Cell Physiol, October 1, 2000; 279(4): C1198 - C1210. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. S. Herness and X.-D. Sun Characterization of Chloride Currents and Their Noradrenergic Modulation in Rat Taste Receptor Cells J Neurophysiol, July 1, 1999; 82(1): 260 - 271. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 B. D. SCHULTZ, A. K. SINGH, D. C. DEVOR, and R. J. BRIDGES Pharmacology of CFTR Chloride Channel Activity Physiol Rev, January 1, 1999; 79(1): 109 - 144. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
W. Zeng, M. G. Lee, and S. Muallem Membrane-specific Regulation of Cl- Channels by Purinergic Receptors in Rat Submandibular Gland Acinar and Duct Cells J. Biol. Chem., December 26, 1997; 272(52): 32956 - 32965. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. A. Martiney, A. Cerami, and A. F. G. Slater Verapamil Reversal of Chloroquine Resistance in the Malaria Parasite Plasmodium falciparum Is Specific for Resistant Parasites and Independent of the Weak Base Effect J. Biol. Chem., September 22, 1995; 270(38): 22393 - 22398. [Abstract] [Full Text] [PDF]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
