FASEB J.
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Blackman, C. F.
Right arrow Articles by House, D. E.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Blackman, C. F.
Right arrow Articles by House, D. E.

The FASEB Journal, Vol 7, 801-806, Copyright © 1993 by The Federation of American Societies for Experimental Biology

RESEARCH COMMUNICATIONS

Evidence for direct effect of magnetic fields on neurite outgrowth

CF Blackman, SG Benane and DE House
Health Effects Research Laboratory, U.S. Environmental Protection Agency, Research Triangle Park, North Carolina 27711-2055.

Electric fields can cause changes in cell responses both in vitro and in vivo. Alternating magnetic fields have been proposed to act through the electric fields induced in the conducting medium surrounding the cells. We have used a simple exposure system to test the relative contribution of magnetic fields compared to induced electric fields in a standard PC-12 cell culture assay, in which cells respond to nerve growth factor by producing neurites. This response to stimulation by nerve growth factor is inhibited by sinusoidal, 50-Hz magnetic fields at field strengths below 10 microT (100 mG). A standard procedure to distinguish magnetic- vs. electric-field effects demonstrates that the induced electric field is not involved. Additional work is necessary to identify the critical reaction site (or sites), and to establish the molecular mechanisms responsible for these results.


This article has been cited by other articles:


Home page
 FASEB J.Home page
A. Lacy-hulbert, J. C. Metcalfe, and R. Hesketh
Biological responses to electromagnetic fields
FASEB J, April 1, 1998; 12(6): 395 - 420.
[Abstract] [Full Text]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1993 by The Federation of American Societies for Experimental Biology.