FASEB J.
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Walleczek, J.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Walleczek, J.

The FASEB Journal, Vol 6, 3177-3185, Copyright © 1992 by The Federation of American Societies for Experimental Biology

REVIEWS

Electromagnetic field effects on cells of the immune system: the role of calcium signaling

J Walleczek
Research Medicine and Radiation Biophysics Division, Lawrence Berkeley Laboratory, University of California 94720.

During the past decade considerable evidence has accumulated demonstrating that nonthermal exposures of cells of the immune system to extremely low-frequency (ELF) electromagnetic fields (< 300 Hz) can elicit cellular changes that might be relevant to in vivo immune activity. A similar responsiveness to nonionizing electromagnetic energy in this frequency range has also been documented for tissues of the neuroendocrine and musculoskeletal system. However, knowledge about the underlying biological mechanisms by which such fields can induce cellular changes is still very limited. It is generally believed that the cell membrane and Ca(2+)-regulated activity is involved in bioactive ELF field coupling to living systems. This article begins with a short review of the current state of knowledge concerning the effects of nonthermal levels of ELF electromagnetic fields on the biochemistry and activity of immune cells and then closely examines new results that suggest a role for Ca2+ in the induction of these cellular field effects. Based on these findings it is proposed that membrane- mediated Ca2+ signaling processes are involved in the mediation of field effects on the immune system.


This article has been cited by other articles:


Home page
 Physiol. Rev.Home page
A. B. Parekh and J. W. Putney Jr.
Store-Operated Calcium Channels
Physiol Rev, April 1, 2005; 85(2): 757 - 810.
[Abstract] [Full Text] [PDF]

Home page
 Indoor and Built EnvironmentHome page
M. Bastide, B.J. Youbicier-Simoa, J.C. Lebecq, and J. Giaimis
Toxicologic Study of Electromagnetic Radiation Emitted by Television and Video Display Screens and Cellular Telephones on Chickens and Mice
Indoor and Built Environment, September 1, 2001; 10(5): 291 - 298.
[Abstract] [PDF]

Home page
 CarcinogenesisHome page
R. M. Ansari and T. K. Hei
Effects of 60 Hz extremely low frequency magnetic fields (EMF) on radiation- and chemical-induced mutagenesis in mammalian cells
Carcinogenesis, June 1, 2000; 21(6): 1221 - 1226.
[Abstract] [Full Text] [PDF]

Home page
 FASEB J.Home page
M. R. CHO, H. S. THATTE, M. T. SILVIA, and D. E. GOLAN
Transmembrane calcium influx induced by ac electric fields
FASEB J, April 1, 1999; 13(6): 677 - 683.
[Abstract] [Full Text]

Home page
 FASEB J.Home page
A. Lacy-hulbert, J. C. Metcalfe, and R. Hesketh
Biological responses to electromagnetic fields
FASEB J, April 1, 1998; 12(6): 395 - 420.
[Abstract] [Full Text]

Home page
 Journal of Bioactive and Compatible PolymersHome page
M. Fini, G. Morrone, R. Giardino, G. Ferioli, M. Mattioli-Belmonte, S. Amati, C. Tietz, G. Biagini, M. M. Tappa, and G. Ricotti
Biological Effects of Tissue Modulations in Wound Healing
Journal of Bioactive and Compatible Polymers, April 1, 1995; 10(2): 85 - 102.
[Abstract]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1992 by The Federation of American Societies for Experimental Biology.