| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
|
|
|
|||||||
|
|||||||||
The FASEB Journal, Vol 5, 2292-2299, Copyright © 1991 by The Federation of American Societies for Experimental Biology
REVIEWS |
Y Shimizu and S Shaw
Experimental Immunology Branch, National Cancer Institute, Bethesda, Maryland 20892.
To mediate an immune response, lymphocytes must be able to interact with and respond to the surrounding extracellular environment. In addition to cell surface molecules that facilitate adhesion of lymphocytes to other cells, recent studies have demonstrated that lymphocytes interact with glycoproteins and glycosaminoglycans that are major components of the extracellular matrix (ECM). Although many receptors mediating the effects of ECM components on lymphocyte function remain poorly defined, a number of lymphocyte ECM receptors have recently been identified; these include members of the integrin family of adhesion molecules as well as structurally unrelated molecules such as CD44 and CD26. Furthermore, as lymphocytes must be able to move between various microenvironments in vivo, they have proved to be an excellent cell type in which to identify and analyze various modes of regulation of cell-ECM interactions. As with other cell types, the ECM has been shown to have multiple effects on lymphocytes; functional analysis reveals effects of the ECM on lymphocyte migration, recognition/activation, and differentiation. These studies emphasize: 1) the importance of lymphocytes as a model system for identifying and analyzing ECM receptor expression and function, and 2) the multiple roles that the ECM plays in the function of the immune system in vivo.
This article has been cited by other articles:
|
|
 |
|
  G. Gorfu, I. Virtanen, M. Hukkanen, V.-P. Lehto, P. Rousselle, E. Kenne, L. Lindbom, R. Kramer, K. Tryggvason, and M. Patarroyo Laminin isoforms of lymph nodes and predominant role of {alpha}5-laminin(s) in adhesion and migration of blood lymphocytes J. Leukoc. Biol., September 1, 2008; 84(3): 701 - 712. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 A. Zanin-Zhorov, G. Tal-Lapidot, L. Cahalon, M. Cohen-Sfady, M. Pevsner-Fischer, O. Lider, and I. R. Cohen Cutting Edge: T Cells Respond to Lipopolysaccharide Innately via TLR4 Signaling J. Immunol., July 1, 2007; 179(1): 41 - 44. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 T. Skripuletz, A. Schmiedl, J. Schade, S. Bedoui, T. Glaab, R. Pabst, S. von Horsten, and M. Stephan Dose-dependent recruitment of CD25+ and CD26+ T cells in a novel F344 rat model of asthma Am J Physiol Lung Cell Mol Physiol, June 1, 2007; 292(6): L1564 - L1571. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 S. Tsujimura, K. Saito, K. Kohno, and Y. Tanaka Fragmented Hyaluronan Induces Transcriptional Up-regulation of the Multidrug Resistance-1 Gene in CD4+ T Cells J. Biol. Chem., December 8, 2006; 281(49): 38089 - 38097. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 G. P.A. Rice, H.-P. Hartung, and P. A. Calabresi Anti-{alpha}4 integrin therapy for multiple sclerosis: Mechanisms and rationale Neurology, April 26, 2005; 64(8): 1336 - 1342. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. Gendron, J. Couture, and F. Aoudjit Integrin {alpha}2{beta}1 Inhibits Fas-mediated Apoptosis in T Lymphocytes by Protein Phosphatase 2A-dependent Activation of the MAPK/ERK Pathway J. Biol. Chem., December 5, 2003; 278(49): 48633 - 48643. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 T. Fukumori, Y. Takenaka, T. Yoshii, H.-R. C. Kim, V. Hogan, H. Inohara, S. Kagawa, and A. Raz CD29 and CD7 Mediate Galectin-3-Induced Type II T-Cell Apoptosis Cancer Res., December 1, 2003; 63(23): 8302 - 8311. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. K. Majors, R. C. Austin, C. A. de la Motte, R. E. Pyeritz, V. C. Hascall, S. P. Kessler, G. Sen, and S. A. Strong Endoplasmic Reticulum Stress Induces Hyaluronan Deposition and Leukocyte Adhesion J. Biol. Chem., November 21, 2003; 278(47): 47223 - 47231. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
P. Friedl, S. Borgmann, and E.-B. Brocker Amoeboid leukocyte crawling through extracellular matrix: lessons from the Dictyostelium paradigm of cell movement J. Leukoc. Biol., October 1, 2001; 70(4): 491 - 509. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D. Snider and H. Liang Early Intestinal Th1 Inflammation and Mucosal T Cell Recruitment During Acute Graft-Versus-Host Reaction J. Immunol., May 15, 2001; 166(10): 5991 - 5999. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
W. H. Rao, J. M. Hales, and R. D. R. Camp Potent Costimulation of Effector T Lymphocytes by Human Collagen Type I J. Immunol., November 1, 2000; 165(9): 4935 - 4940. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 S. Kokura, R. E. Wolf, T. Yoshikawa, D. N. Granger, and T. Y. Aw Postanoxic T Lymphocyte-Endothelial Cell Interactions Induce Tumor Necrosis Factor-{alpha} Production and Neutrophil Adhesion : Role of Very Late Antigen-4/Vascular Cell Adhesion Molecule-1 Circ. Res., June 23, 2000; 86(12): 1237 - 1244. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 Y. Bouatrouss, F. E. Herring-Gillam, J. Gosselin, J. Poisson, and J.-F. Beaulieu Altered Expression of Laminins in Crohn’s Disease Small Intestinal Mucosa Am. J. Pathol., January 1, 2000; 156(1): 45 - 50. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. Esparza, C. Vilardell, J. Calvo, M. Juan, J. Vives, A. Urbano-Marquez, J. Yague, and M. C. Cid Fibronectin Upregulates Gelatinase B (MMP-9) and Induces Coordinated Expression of Gelatinase A (MMP-2) and Its Activator MT1-MMP (MMP-14) by Human T Lymphocyte Cell Lines. A Process Repressed Through RAS/MAP Kinase Signaling Pathways Blood, October 15, 1999; 94(8): 2754 - 2766. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K. Kamiguchi, K. Tachibana, S. Iwata, Y. Ohashi, and C. Morimoto Cas-L Is Required for {beta}1 Integrin-Mediated Costimulation in Human T Cells J. Immunol., July 15, 1999; 163(2): 563 - 568. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. W. O'Regan, G. L. Chupp, J. A. Lowry, M. Goetschkes, N. Mulligan, and J. S. Berman Osteopontin Is Associated with T Cells in Sarcoid Granulomas and Has T Cell Adhesive and Cytokine-Like Properties In Vitro J. Immunol., January 15, 1999; 162(2): 1024 - 1031. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 D. Taverna, M.-H. Disatnik, H. Rayburn, R. T. Bronson, J. Yang, T. A. Rando, and R. O. Hynes Dystrophic Muscle in Mice Chimeric for Expression of alpha 5 Integrin J. Cell Biol., November 2, 1998; 143(3): 849 - 859. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. S. Duke-Cohan, J. Gu, D. F. McLaughlin, Y. Xu, G. J. Freeman, and S. F. Schlossman Attractin (DPPT-L), a member of the CUB family of cell adhesion and guidance proteins, is secreted by activated human T lymphocytes and modulates immune cell interactions PNAS, September 15, 1998; 95(19): 11336 - 11341. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. Marazzi, S. Blum, R. Hartmann, D. Gundersen, M. Schreyer, S. Argraves, V. von Fliedner, R. Pytela, and C. Ruegg Characterization of Human Fibroleukin, a Fibrinogen-Like Protein Secreted by T Lymphocytes J. Immunol., July 1, 1998; 161(1): 138 - 147. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 P. Ruiz, N. Zacharievich, and M. Shenkin Clin. Vaccine Immunol., May 1, 1998; 5(3): 362 - 368. [Abstract]
|
|
|
|
|
|
M. T. Rock, W. H. Brooks, and T. L. Roszman Calcium-dependent Signaling Pathways in T Cells. POTENTIAL ROLE OF CALPAIN, PROTEIN TYROSINE PHOSPHATASE 1B, AND p130Cas IN INTEGRIN-MEDIATED SIGNALING EVENTS J. Biol. Chem., December 26, 1997; 272(52): 33377 - 33383. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
G. Chi-Rosso, P. J. Gotwals, J. Yang, L. Ling, K. Jiang, B. Chao, D. P. Baker, L. C. Burkly, S. E. Fawell, and V. E. Koteliansky Fibronectin Type III Repeats Mediate RGD-independent Adhesion and Signaling through Activated beta 1 Integrins J. Biol. Chem., December 12, 1997; 272(50): 31447 - 31452. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
E. L. George, H. S. Baldwin, and R. O. Hynes Fibronectins Are Essential for Heart and Blood Vessel Morphogenesis But Are Dispensable for Initial Specification of Precursor Cells Blood, October 15, 1997; 90(8): 3073 - 3081. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 C. Fiocchi Intestinal inflammation: a complex interplay of immune and nonimmune cell interactions Am J Physiol Gastrointest Liver Physiol, October 1, 1997; 273(4): G769 - G775. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C.-H. Hung, H.-R. Huang, C.-J. Huang, F.-L. Huang, and G.-D. Chang Purification and Cloning of Carp Nephrosin, a Secreted Zinc Endopeptidase of the Astacin Family J. Biol. Chem., May 23, 1997; 272(21): 13772 - 13778. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. Rafi, M. Nagarkatti, and P. S. Nagarkatti Hyaluronate-CD44 Interactions Can Induce Murine B-Cell Activation Blood, April 15, 1997; 89(8): 2901 - 2908. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 C. Leung-Hagesteijn, K Milankov, M Michalak, J Wilkins, and S Dedhar Cell attachment to extracellular matrix substrates is inhibited upon downregulation of expression of calreticulin, an intracellular integrin alpha-subunit-binding protein J. Cell Sci., January 3, 1994; 107(3): 589 - 600. [Abstract] [PDF]
|
|
|
|
 |
|
 J. T. Yang, H. Rayburn, and R. O. Hynes Embryonic mesodermal defects in alpha 5 integrin-deficient mice Development, December 1, 1993; 119(4): 1093 - 1105. [Abstract] [PDF]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
