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The FASEB Journal, Vol 5, 55-60, Copyright © 1991 by The Federation of American Societies for Experimental Biology

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Ethical issues in human genome research

TH Murray
School of Medicine, Case Western Reserve University, Cleveland, Ohio 44106.

In addition to provocative questions about science policy, research on the human genome will generate important ethical questions in at least three categories. First, the possibility of greatly increased genetic information about individuals and populations will require choices to be made about what that information should be and about who should control the generation and dissemination of genetic information. Presymptomatic testing, carrier screening, workplace genetic screening, and testing by insurance companies pose significant ethical problems. Second, the burgeoning ability to manipulate human genotypes and phenotypes raises a number of important ethical questions. Third, increasing knowledge about genetic contributions to ethically and politically significant traits and behaviors will challenge our self- understanding and social institutions.


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Copyright © 1991 by The Federation of American Societies for Experimental Biology.