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The FASEB Journal, Vol 4, 1460-1468, Copyright © 1990 by The Federation of American Societies for Experimental Biology
REVIEWS |
JE Rothman and L Orci
Department of Molecular Biology, Princeton University, New Jersey 08544.
A combination of cell-free biochemical and morphological studies has revealed that a coated bud-coated vesicle transport system shuttles newly synthesized proteins through the successive processing compartments of the Golgi apparatus. These Golgi-coated vesicles operate in a manner formally analogous to the clathrin-coated, pit- coated vesicle system responsible for receptor-mediated endocytosis; however Golgi-coated vesicles do not contain clathrin.
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