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The FASEB Journal, Vol 2, 97-107, Copyright © 1988 by The Federation of American Societies for Experimental Biology

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Control strategies in physiological systems

JC Houk
Department of Physiology, Northwestern University Medical Center, Chicago, Illinois 60611.

In this paper, written for a general audience, I review and contrast various strategies that the body uses to control homeostasis and movement. Messages, signals, communication channels, and control systems are dealt with from both a cellular and an integrative perspective. The major global control strategies are feedback, feedforward, and adaptive control, and examples of each are presented to highlight advantageous and disadvantageous features. Many physiological systems use these three strategies in combination.


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Copyright © 1988 by The Federation of American Societies for Experimental Biology.