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(The FASEB Journal. 2002;16:1695-1696.)
© 2002 FASEB

Glyceroneogenesis comes of age

ELMUS G. BEALE*1, ROBERT E. HAMMER{dagger}, BÉNÉDICTE ANTOINE and CLAUDE FOREST

* Department of Cell Biology and Biochemistry, Texas Tech University Health Sciences Center, Lubbock, Texas, USA; Unité mixte Inserm U530-Université Paris 5; Centre Universitaire-U.F.R. Biomédicale; 75006 Paris; and
{dagger} University of Texas Southwestern Medical Center at Dallas, Howard Hughes Medical Institute and Department of Biochemistry, Dallas, Texas, USA

1Correspondence: Department of Cell Biology and Biochemistry, Stop 6540, Texas Tech University Health Sciences Center, Lubbock, TX 79430, USA. E-mail: elmus.beale{at}ttuhsc.edu

Glyceroneogenesis is a generally ignored metabolic pathway that occurs in adipose tissues and liver of mammalian species. This short review highlights a series of recent discoveries showing that glyceroneogenesis is important in lipid homeostasis.—Beale, E. G., Hammer, R. E., Antoine, B., Forest, C. Glyceroneogenesis comes of age.


Key Words: phosphoenolpyruvate carboxykinase • lipid homeostasis • obesity • diabetes




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