Figure 1. Immunohistochemical localization of the GFP in mouse ileum, liver and spleen. A–C) Sections of the ileum of the mice fed with CTB-GFP expressing plant leaf. Arrows indicate presence of GFP in the intestinal epithelium as well as cells of the crypts. D) Shows a section of the ileum of a mouse fed with wild-type (untransformed) plant leaf materials. E) GFP- immunoreactivity in hepatocytes (arrows) in a mouse fed orally with CTB-GFP expressing plant. F) Section of the liver from a mouse fed with wild-type (untransformed) plant. G) Section of the liver from a mouse fed with IFN-GFP expressing plant. H) GFP-immunoreactivity in the spleen of mouse fed orally with CTB-GFP expressing plant. Arrows indicate various cells with a higher GFP content. I) Section of the spleen from a mouse fed with wild-type (untransformed) plant. J) Section of the spleen from a mouse fed with IFN-GFP expressing plant. Scale bar for A–D = 50 µm. Scale bar for E–J = 25 µm.