Figure 1. Pathological leakage resembling CNV formation two weeks after laser photocoagulation. Representative angiograms (A) from the early (1–3 min) and the late (6–8 min) phase after fluorescein injection. A large and diffuse area of leakage was observed in WT mice. In FasL transgenic mice, CNV lesions were less severe. B) Area of fluorescein leakage (mm²). A significant reduction of leakage areas is observed in FasL transgenic mice compared with WT mice.