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Contact: Cody Mooneyhan
cmooneyhan{at}faseb.org

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Stem cell breakthrough: Bone marrow cells are the answer
New research in The FASEB Journal shows that bone marrow cells fuse to different types of cells, including embryonic stem cells, creating new hybrids that may evade immune rejection
Bethesda, MD—Using cells from mice, scientists from Iowa and Iran have discovered a new strategy for making embryonic stem cell transplants less likely to be rejected by a recipient's immune system. This strategy involves fusing bone marrow cells to embryonic stem cells. Once fused, the hybrid cells have DNA from both the donor and recipient, raising hopes that immune rejection of embryonic stem cell therapies can be avoided without drugs. [View Release]

New finding may help baby boomers get buff
New research in The FASEB Journal shows free radicals damage mitochondria in our muscle cells, resulting in age-related muscle loss
Bethesda, MD—If you're an aging baby boomer hoping for a buffer physique, there's hope. A team of American scientists from Texas and Michigan have made a significant discovery about the cause of age-related muscle atrophy that could lead to new drugs to halt this natural process. This research shows that free radicals, such as reactive oxygen species, damage mitochondria in muscle cells, leading to cell death and muscle atrophy. Now that scientists understand the cause of age-related muscle loss, they can begin to develop new drugs to halt the process. [View Release]

Finally, an excuse for pregnant women to eat bacon and eggs
New epigenetic study in The FASEB Journal shows a link between maternal diet and brain development in gestating mice
Bethesda, MD—If you're pregnant and looking for an excuse to eat bacon and eggs, now you've got one: new research by a team of University of North Carolina researchers shows that choline plays a critical role in helping fetal brains develop regions associated with memory. Choline is found in meats, including pork, as well as chicken eggs. [View Release]

New year, new vitamin C discovery: It 'cures' mice with accelerated aging disease
New research in The FASEB Journal reports vitamin C reverses abnormalities caused by Werner syndrome gene, including cancer, obesity, diabetes, heart failure and high cholesterol
Bethesda, MD—A new research discovery suggests that treatments for disorders that cause accelerated aging, particularly Werner's syndrome, might come straight from the family medicine chest. In the research report, a team of Canadian scientists show that vitamin C stops and even reverses accelerated aging in a mouse model of Werner's syndrome, but the discovery may also be applicable to other progeroid syndromes. People with Werner's syndrome begin to show signs of accelerated aging in their 20s and develop age-related diseases and generally die before the age of 50. [View Release]

New discovery by Harvard scientists aims to correct cellular defects leading to diabetes
New research in The FASEB Journal reports that the G6PD protein, which produces the essential antioxidant NAPDH, could prevent the death of pancreatic beta cells, the root cause of diabetes
Bethesda, MD—A new research discovery may change the perception and treatment of diabetes. That's because scientists have moved closer toward correcting the root cause of the disease rather than managing its symptoms. Specifically researchers identified a protein (G6PD protein) and its antioxidant product (NAPDH) that both prevent the death and promote the growth of cells which produce and release insulin in the pancreas (beta cells). [View Release]

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